ID   K1S6W3_CRAGI            Unreviewed;       852 AA.
AC   K1S6W3;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Patched domain-containing protein 3 {ECO:0000313|EMBL:EKC43181.1};
GN   ORFNames=CGI_10027279 {ECO:0000313|EMBL:EKC43181.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC43181.1};
RN   [1] {ECO:0000313|EMBL:EKC43181.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC43181.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   EMBL; JH817465; EKC43181.1; -; Genomic_DNA.
DR   RefSeq; XP_011442864.1; XM_011444562.2.
DR   AlphaFoldDB; K1S6W3; -.
DR   GeneID; 105339142; -.
DR   KEGG; crg:105339142; -.
DR   HOGENOM; CLU_002359_2_1_1; -.
DR   InParanoid; K1S6W3; -.
DR   OMA; SEEFPYW; -.
DR   OrthoDB; 2876883at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF92; PATCHED-RELATED, ISOFORM A; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   852 AA;  94504 MW;  868DA4F0D497A93D CRC64;
     MGDCYVRHED RIARIFGMYG KFLERHPVKI LVISITVNCL LGLGMLRLEV ESGAERLYTP
     VNSQASKDRS FLENIYPSSS EFYAHKETAD FAEVLILTKD RGNMLTSTFL DDVTSVDEFV
     RNSISITQSG TVYKFSDVCA KQSSACVVSG DIVLSSEFKQ MMLANNITYP EFNQTSISSL
     FASPSASNGV LTSAIGLKLT YYLRSSYSEQ WEKEFVKTIP NAVVNISELA YSYSDALDNE
     LEENIGGDIL FYSLTMTFMM TYACIATSRL NGNCIADRSL LGQAGVLAAV LSILSSFGFV
     SLIGVKFMSI VGVMPFLIIG IGIDDVFILM SGIADAESIE KSSVSDRISF MMRTSGIAIT
     ITSITDFLAF SIGASSVFIS VRNFCIYTGV AVLFCYINQI TIFSSCIVIN EKRIKDNRHC
     VACWTRTKDK ESLQMDGKTG CSLYACAGYP PKDRSDVDSP LEKYPKRLIQ FVMKYLVLKI
     AILVIFAIYL GFSIYGVVHL DQGLSLQNLV TEDSFFYKYS MWRENYFRSE VVMSFNVKTT
     QTYSSSWTQG IIASILTTAK QDKDIDPSFE LNWLTAFKQS ALYVDTSESA FITALQTFLT
     NVPLYASDVV IDSSGPSITS SRFYLKTNNI PSTYDQGQMM LRMREVTANS AIPMIVYSPP
     FIFFEQFVEI LPSTLQTVGI AIVVIIIVTI LFMPHPTLII IVGVTLFTIL LGVFGFMFFW
     DISLSSISMI HLVMTVGFSV DFSAHICHAY LAVDADDRAT KVDLSLDRSG GPIFNAAFST
     LLGVSILGFA NSYIFKTFGK MMFLVIFFGL AHSVLLIPTV LSFIGPLKAR KVKPDEKAQL
     ERENSKSSSS PI
//