ID   K1S6Z0_CRAGI            Unreviewed;      1545 AA.
AC   K1S6Z0;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
GN   ORFNames=CGI_10027320 {ECO:0000313|EMBL:EKC43221.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC43221.1};
RN   [1] {ECO:0000313|EMBL:EKC43221.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC43221.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
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DR   EMBL; JH817465; EKC43221.1; -; Genomic_DNA.
DR   HOGENOM; CLU_246646_0_0_1; -.
DR   InParanoid; K1S6Z0; -.
DR   OMA; AFNSHIN; -.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 2.60.220.30; -; 2.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   PANTHER; PTHR28336; BA1-643; 1.
DR   PANTHER; PTHR28336:SF4; DEATH DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00531; Death; 2.
DR   SMART; SM00005; DEATH; 2.
DR   SUPFAM; SSF47986; DEATH domain; 2.
DR   PROSITE; PS50017; DEATH_DOMAIN; 2.
PE   4: Predicted;
FT   DOMAIN          1357..1444
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   DOMAIN          1477..1545
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
SQ   SEQUENCE   1545 AA;  174096 MW;  4960A19B043D704C CRC64;
     MNQIQNDNID KSLKAINSYQ SGSNGDSQGG KTLTNESEDQ KSHSEELSTG KRSSIEVSGQ
     DLSESPDSQK LNAEENIAPQ SNNNGLENGD NSTFKEDISE KDGSPRELSN GGSKGDEKLL
     NETEDSVDGA NKREVESEIG DKVNTEKSQT NVDEHDKSVE KEESNTFITN LPADEYADNT
     TEEFGNKDKA LDNDEREPQG QPENSEQNNT QTENITQQDD FYDESPQKSV PSENSETKDK
     ELIHESNTGG KEGGGDRAEY LTTGQQNPTD VTDGNTDDVL KTNTVSDPSE QKEGVQEEAC
     VSDREQEKSE KDKEETKISE REQEKSDKSS LKSVNKEEAN LSEEPKAETK EETKQASKVS
     SESYAEGDQS SSSSSTKQDD TLADVDPLET LAETPVKADK EGIESEMTKS EVERSADDNA
     RADDVSKRVI NDDTDNEADD LKSEEVTQTK ESNNNMEEIV QRESSETQNE PKDDSKQTDN
     DDDGSPKEVS DSTNINKNTE QGEINEDEAV QRKDGDDKEE NEEKDAEKED KTPDDVEEPV
     TNENAEQPVT HESPKEPEEN HVVREPTPEP EPEPEPVKVF RNIDIDNAVT TIQDTEGPLK
     NLLSDMKELL TNYQDKLNSE MLSDFTKDLD KFRGDFASLK DAFHYSEELF HYFNKNLKEI
     RMLGDNLNSL IQKKFRMEDL TVWLESPEAR MEEKDALMEE RISVEKSAMA KAADARAAIA
     RAAVSVTESS LFAAEIEAEA AEAEAVSRRA WETAQNAKRD VEEAEKAAVE KRKAEEEARK
     RAEERAQKKA EEERLRQAEE NERLKEEADK KGTSYEDEKR RFQEEKARKE AERKNPKNWP
     RYIYSVDSST IEAGVPGCVI RAIEGSMKRD DVTVKAVDQL SGVLTLVENE ELVSNIVSIT
     PSDPERKFQF EEPVSVAIPH CLQRNIPGRE PVIKQLQPTG KWAELPTNDI VIEDMREMKF
     VEIRVKRFGV FAIVLRIKKD TLTFLRRGNK VNSSVDARIS FTCKPGMVKN NVCFTSEVQA
     LDVNTVTELN KRYPTECGSL LSSSPIVRFQ IPNRKFAKPL TFTLPLPPNS TKLKRPQSVA
     PGSLNKDKGE HREQAAARPL SSIGFSTKED EPEEEMHLLV REDKGPWTIQ PNVELFQPKN
     KDIVTFDIKE PHDRFIILRT KQGISPLSVE KMASHVERAI HHRTMQVVLR QRSDDPNEVV
     IVCCPASRTD KTIKILGEEG FDEGPPPSKD IIVKEGQILD IMFRGNIRCD DAEKISIVFN
     TFIRGRTEFN VEEIDKFAQK SFSFYRGFAQ VYTTVHVQRP VVGTDKTKAP QKPGAMEVVE
     ENVLLTELLI NIPKPEPEPP KPLATAPIKV TAEGPNKEDI LQYVASELGD EWKKLAQYLS
     LKSVRIQAIL RQNNQNPEPK KIRYDMLVTW AKRVPRCLNK LEILAQALSA CGRGDLAIDL
     RERDEEFRRR RALAFRDSYL RRAFVKIAQN PEAVKGWKTL ATRLGVSEDD VTEIDQSGPS
     VQQKCFSSLQ RWQRSAGDEA TLPILSEKLR VCRYRQLARD IETIA
//