ID K1VMH1_TRIAC Unreviewed; 855 AA.
AC K1VMH1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Multi-sensor hybrid histidine kinase {ECO:0000313|EMBL:EKD05385.1};
GN ORFNames=A1Q2_00315 {ECO:0000313|EMBL:EKD05385.1};
OS Trichosporon asahii var. asahii (strain CBS 8904) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Trichosporonales; Trichosporonaceae; Trichosporon.
OX NCBI_TaxID=1220162 {ECO:0000313|EMBL:EKD05385.1, ECO:0000313|Proteomes:UP000006757};
RN [1] {ECO:0000313|EMBL:EKD05385.1, ECO:0000313|Proteomes:UP000006757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 8904 {ECO:0000313|EMBL:EKD05385.1,
RC ECO:0000313|Proteomes:UP000006757};
RX PubMed=23193141; DOI=10.1128/EC.00264-12;
RA Yang R.Y., Li H.T., Zhu H., Zhou G.P., Wang M., Wang L.;
RT "Genome sequence of the Trichosporon asahii environmental strain CBS
RT 8904.";
RL Eukaryot. Cell 11:1586-1587(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD05385.1}.
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DR EMBL; AMBO01000103; EKD05385.1; -; Genomic_DNA.
DR AlphaFoldDB; K1VMH1; -.
DR STRING; 1220162.K1VMH1; -.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_334058_0_0_1; -.
DR InParanoid; K1VMH1; -.
DR OrthoDB; 2734979at2759; -.
DR Proteomes; UP000006757; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF6; RESPONSE REGULATORY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EKD05385.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000006757};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 248..478
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 641..758
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..833
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..855
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 691
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 855 AA; 92945 MW; DE8A828C3F3230F1 CRC64;
MPDHIPVARR PSMSTLSVTG ETMTTSSQAP NGGGETLSSS QDTQTLSERD QLDTLALMRS
SLALAQEKDS LVLLCTLLKI LCQFMRCDYA AIGLTDEGDR SVLRLKAAGP FQRILPYDLD
VAEVSAQTVC PTSIMLHVSR TGIPITQPAK AFRLRNDPFF DDRQPRMLMC LPVINQGIQS
GVILLMSMSN AATALQSESA REVISTLATF AYIIHMHHVF TSRLKTEVTM RTRELTAALQ
AKTLFLSQCS HELRSPLAAI MGLAAVLENS AGLTPVQREH LGTILTSGND LLALISNILD
HSKLESNSVL LEHIPFSVRD VVESALDTVA PVAQSKNVEL TVLSIFRNDP PGLLGDPFRV
KQVVLNLLSN AVKFTPPGER GKRTARVTVE RMWEDLGDGQ IKIILAVEDT GVGIPASKLN
KLFKSFSQVD ESITRSYGGS GLGLVISRDL ACLLGGDCTV ESEFGKGSKF TFSFVGTRDP
NWKPTVIRRF PQPKRIFVLC SRDMVWGRLL EEDSKEFNCI PTRFVDDAKL ALDPGRVNGL
NSGIEYAFIL IDAPAVDLET LTRMRELQPR AKFLFVTRIT EIAAEMDRLQ LSRESILARP
LKFKSVHDAI IPEDTPKGGN LPAPKAKRPI NKQLGKDKPL TVLVVDDAPV NIQVCRRILE
LYGYKDVDSA TDGLQATELA EKRRYDLILL DLQMPVLDGF GALERIKASP LAGEPCCVSL
SANVDKATRD RCSDVGFFAV LDKPVDIPRL GEILIKVHNH RNGLPTDQPT SPKVSALLSP
KTSPTLSPKV SHSDSATPKP SVNCTASSPT LSPKASRGDQ ITSTAQSNDA EPPSPSATPK
PTPAVNANAS ANGTV
//
