ID K1W6S4_TRIAC Unreviewed; 667 AA.
AC K1W6S4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN ORFNames=A1Q2_08210 {ECO:0000313|EMBL:EKC97473.1};
OS Trichosporon asahii var. asahii (strain CBS 8904) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Trichosporonales; Trichosporonaceae; Trichosporon.
OX NCBI_TaxID=1220162 {ECO:0000313|EMBL:EKC97473.1, ECO:0000313|Proteomes:UP000006757};
RN [1] {ECO:0000313|EMBL:EKC97473.1, ECO:0000313|Proteomes:UP000006757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 8904 {ECO:0000313|EMBL:EKC97473.1,
RC ECO:0000313|Proteomes:UP000006757};
RX PubMed=23193141; DOI=10.1128/EC.00264-12;
RA Yang R.Y., Li H.T., Zhu H., Zhou G.P., Wang M., Wang L.;
RT "Genome sequence of the Trichosporon asahii environmental strain CBS
RT 8904.";
RL Eukaryot. Cell 11:1586-1587(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKC97473.1}.
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DR EMBL; AMBO01000410; EKC97473.1; -; Genomic_DNA.
DR AlphaFoldDB; K1W6S4; -.
DR STRING; 1220162.K1W6S4; -.
DR eggNOG; KOG1716; Eukaryota.
DR HOGENOM; CLU_023312_4_0_1; -.
DR InParanoid; K1W6S4; -.
DR OMA; CCGCKEW; -.
DR OrthoDB; 5472710at2759; -.
DR Proteomes; UP000006757; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14498; DSP; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR45848:SF4; DUAL SPECIFICITY PROTEIN PHOSPHATASE 12; 1.
DR PANTHER; PTHR45848; DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000006757}.
FT DOMAIN 117..278
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 200..257
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 72376 MW; 6C3638838C15D146 CRC64;
MTAQTAHATP KRALSRRPSL PERTKMTMTD LPPADAQKPD SLAVDDVFDQ LKATGSLEAA
ARRLAEIAMR EETLPKVVQR RQAWEDDPEE AEWQQQQAEE AQGGAARRGE EEEEIEHLQQ
VCDGLWVGDL VAAMDGEGLR ERGISNVVSL LRPRLNFDPE FAAYTIEIDD AQDTDILQFL
PSTSAWIRDA LLKRQGTPDE ERDPAIEPRA PETNPGGVLV HCQAGMSRSA TVAAAFLMNE
LELDPEDAVQ VVRDARPVVD PSETFWHQLG IYHQAKKRVT MKDRTTRQFY LERNAGMVLN
LGGRPSMDHM AKYPLSPTAS TPQTPAGATG RRKIRCKMCR RNLATREHMM DHILAQSGGP
ATRPATPSAF ALPQPLTTTE DATFQPLERS NSVSSVINPL TGLPGARSRR ASNASSRRPS
LGAMSAISDG TTRSRSRSVL GNDGQLTMSR RDSSGSATGP SGLAPMTSPE AVKSEGGRPP
TPPLPSDSKK EEKEPKEHKE EKKEEKKGPG GRPMLDADAL AARLPPQLAA LRAGFSATSN
LSSPIASSPP SSPESELPPA RRRPSNLGMT SMPQPLTPAA LSALTQAHAQ QAAQNGPPIL
TNNKCSGYFV EPLTWMEPAL NGQVSGKLFC PCGAKIGTFD WAGVQCGCKE WVTPGFCIHR
SRVDEVW
//
