ID K1WFB2_TRIAC Unreviewed; 564 AA.
AC K1WFB2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=A1Q2_05426 {ECO:0000313|EMBL:EKD00249.1};
OS Trichosporon asahii var. asahii (strain CBS 8904) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Trichosporonales; Trichosporonaceae; Trichosporon.
OX NCBI_TaxID=1220162 {ECO:0000313|EMBL:EKD00249.1, ECO:0000313|Proteomes:UP000006757};
RN [1] {ECO:0000313|EMBL:EKD00249.1, ECO:0000313|Proteomes:UP000006757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 8904 {ECO:0000313|EMBL:EKD00249.1,
RC ECO:0000313|Proteomes:UP000006757};
RX PubMed=23193141; DOI=10.1128/EC.00264-12;
RA Yang R.Y., Li H.T., Zhu H., Zhou G.P., Wang M., Wang L.;
RT "Genome sequence of the Trichosporon asahii environmental strain CBS
RT 8904.";
RL Eukaryot. Cell 11:1586-1587(2012).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC {ECO:0000256|ARBA:ARBA00005755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD00249.1}.
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DR EMBL; AMBO01000345; EKD00249.1; -; Genomic_DNA.
DR AlphaFoldDB; K1WFB2; -.
DR STRING; 1220162.K1WFB2; -.
DR eggNOG; KOG0968; Eukaryota.
DR HOGENOM; CLU_000203_4_1_1; -.
DR InParanoid; K1WFB2; -.
DR OMA; AYNMCYS; -.
DR OrthoDB; 211439at2759; -.
DR Proteomes; UP000006757; Unassembled WGS sequence.
DR GO; GO:0016035; C:zeta DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0019985; P:translesion synthesis; IEA:InterPro.
DR CDD; cd05534; POLBc_zeta; 1.
DR Gene3D; 1.10.132.60; DNA polymerase family B, C-terminal domain; 1.
DR Gene3D; 1.10.287.690; Helix hairpin bin; 1.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR042087; DNA_pol_B_thumb.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR InterPro; IPR030559; PolZ_Rev3.
DR InterPro; IPR025687; Znf-C4pol.
DR PANTHER; PTHR45812; DNA POLYMERASE ZETA CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR45812:SF1; DNA POLYMERASE ZETA CATALYTIC SUBUNIT; 1.
DR Pfam; PF00136; DNA_pol_B; 1.
DR Pfam; PF14260; zf-C4pol; 1.
DR PRINTS; PR00106; DNAPOLB.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00023204};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932};
KW Reference proteome {ECO:0000313|Proteomes:UP000006757};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT DOMAIN 10..420
FT /note="DNA-directed DNA polymerase family B
FT multifunctional"
FT /evidence="ECO:0000259|Pfam:PF00136"
FT DOMAIN 465..534
FT /note="C4-type zinc-finger of DNA polymerase delta"
FT /evidence="ECO:0000259|Pfam:PF14260"
SQ SEQUENCE 564 AA; 62618 MW; B151C11E3AA64FED CRC64;
MVTPSKQQVG LQNAPFAVPL IHEPESKYYN HPIIVLDFQS LYPSVMIAYN ICYSTCLGRV
EQFKGTNKFG FTELKVPDGL LELLKDYLTV TPNGMIFVKP AVRKSLLAKM LGEILDTRVM
VKQAMKGYRD NKSLTQMLNA RQLGLKLMAN VTYGYTSATY SGRMPCIEIA DSIVQTGRET
LEKAQELINS EAKWGATVVY GDTDSLFVAL PGRSKDEAFK IGHDIADAVT AMNPKPVKLK
FEKVYMGSVL MAKKRYVGFK YEHPDDVDPV FDAKGIETIR RDGFPAQQKI EEIALKMLFK
NQDLSEIKAF VQDEWRKVLT GRVSLQDFIV AKEVRLGTYS EKGVPPPGAA VAYRRILKDP
RDEVEYGERV PYIISDSSTG GKRLIDKART PEEMLSSNLG IDKEYYIRNL LIPPLSRIFN
LVGADVEQWY DSMPRSKRVS TYGANGGGGS ARTTRIDAHF RSRHCLVCGA ESGDALCAAC
RDEPAATAHA LLSRQHAAHS RLAELQRICA SCAGTGPAER VLCDSIDCSA LYARARAEKD
VTDVADVPAL VAELDQQDTL DLDW
//
