ID K1WP87_MARBU Unreviewed; 636 AA.
AC K1WP87;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 22-FEB-2023, entry version 36.
DE RecName: Full=Solute carrier family 40 member {ECO:0000256|RuleBase:RU365065};
GN ORFNames=MBM_02717 {ECO:0000313|EMBL:EKD19480.1};
OS Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Drepanopezizaceae; Drepanopeziza.
OX NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD19480.1, ECO:0000313|Proteomes:UP000006753};
RN [1] {ECO:0000313|EMBL:EKD19480.1, ECO:0000313|Proteomes:UP000006753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB_m1 {ECO:0000313|EMBL:EKD19480.1,
RC ECO:0000313|Proteomes:UP000006753};
RX PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA Huang M.-R., Wu R., Zhou Y.;
RT "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT evolution.";
RL BMC Genomics 13:382-382(2012).
CC -!- FUNCTION: May be involved in iron transport and iron homeostasis.
CC {ECO:0000256|RuleBase:RU365065}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365065}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365065}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000256|ARBA:ARBA00006279,
CC ECO:0000256|RuleBase:RU365065}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365065}.
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DR EMBL; JH921431; EKD19480.1; -; Genomic_DNA.
DR RefSeq; XP_007290606.1; XM_007290544.1.
DR AlphaFoldDB; K1WP87; -.
DR GeneID; 18758652; -.
DR KEGG; mbe:MBM_02717; -.
DR eggNOG; KOG2601; Eukaryota.
DR HOGENOM; CLU_020370_2_0_1; -.
DR InParanoid; K1WP87; -.
DR OMA; ISARRVW; -.
DR OrthoDB; 38357at2759; -.
DR Proteomes; UP000006753; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11660; SOLUTE CARRIER FAMILY 40 MEMBER; 1.
DR PANTHER; PTHR11660:SF57; SOLUTE CARRIER FAMILY 40 PROTEIN; 1.
DR Pfam; PF06963; FPN1; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EKD19480.1};
KW Ion transport {ECO:0000256|RuleBase:RU365065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365065};
KW Reference proteome {ECO:0000313|Proteomes:UP000006753};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365065};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365065};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365065}.
FT TRANSMEM 123..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 147..171
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 374..407
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 439..461
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT TRANSMEM 565..585
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365065"
FT REGION 28..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 69433 MW; FD817EC0371F096F CRC64;
MVPRIIIQRP SISSDDLGSH WEYASRDERE DAADARSVGA QHGEMRRRSQ DSTFDVDGEQ
LWRARMSIDA EMELARGQRM KWWKVYAMHF LFMWNTRTYE YVSIFLVALA FPGSLTATSI
RGMASTVSTM IFASAVGNWI DKSPSRLPNL LTTIGLNHVV IVASYICWLF WPVVAGRGDE
AGGPSAGPFS NLAKGLLYTF ILLLDVVHDL TAIANHLSVE RDWVPVLVGP DTKYTLTEVN
AVMVRLELVC KLIAPSMLPV IVKSFHSQTG WILLLTGLTV FLWAVEVQCA RMISRENPEL
QVPKKLSNDF ATGDLFGIQK PGVTTVAQKL YAVLYHDPAV RLRHYFSISI WPASISMALL
QLTVLAYSST LITYLFGIGF SLVAITLAQA SGSIVSLSST VITPFAVKFL RRRYARAARS
DDDEAEDEEN GEGKIARRVG FWGIASQFLC LIPVALVLWS LSPPQPSLAT TTTTTTTTTT
TTTSSSPPVP LSLSLSLLLF LSLSLSRLGH HACQLMVQQL GQVEIPMSQR STFAGTETSF
KALGSLGHYA ATAVWSSSRP EDFRWLALGS VLVIGAATGL FGSWARRRPI VSGMSGGSGR
ERGQRYEGVA MEDVDGGGGG YGGGGGDGYG EYHHRG
//
