ID   K1WQC6_MARBU            Unreviewed;       968 AA.
AC   K1WQC6;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   22-FEB-2023, entry version 49.
DE   RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE            EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN   ORFNames=MBM_07298 {ECO:0000313|EMBL:EKD14577.1};
OS   Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS   spot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Drepanopezizaceae; Drepanopeziza.
OX   NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD14577.1, ECO:0000313|Proteomes:UP000006753};
RN   [1] {ECO:0000313|EMBL:EKD14577.1, ECO:0000313|Proteomes:UP000006753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MB_m1 {ECO:0000313|EMBL:EKD14577.1,
RC   ECO:0000313|Proteomes:UP000006753};
RX   PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA   Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA   Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA   Huang M.-R., Wu R., Zhou Y.;
RT   "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT   evolution.";
RL   BMC Genomics 13:382-382(2012).
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU01016}.
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DR   EMBL; JH921445; EKD14577.1; -; Genomic_DNA.
DR   RefSeq; XP_007295187.1; XM_007295125.1.
DR   AlphaFoldDB; K1WQC6; -.
DR   STRING; 1072389.K1WQC6; -.
DR   GeneID; 18763233; -.
DR   KEGG; mbe:MBM_07298; -.
DR   eggNOG; ENOG502RYYW; Eukaryota.
DR   HOGENOM; CLU_012943_2_2_1; -.
DR   InParanoid; K1WQC6; -.
DR   OMA; RIESTIC; -.
DR   OrthoDB; 1948937at2759; -.
DR   Proteomes; UP000006753; Unassembled WGS sequence.
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR018117; C5_DNA_meth_AS.
DR   InterPro; IPR001525; C5_MeTfrase.
DR   InterPro; IPR031303; C5_meth_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR   Pfam; PF00145; DNA_methylase; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00094; C5_MTASE_1; 1.
DR   PROSITE; PS00095; C5_MTASE_2; 1.
DR   PROSITE; PS51679; SAM_MT_C5; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000006753};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01016};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01016}.
FT   REGION          70..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          518..556
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          622..653
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        628..645
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        731
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ   SEQUENCE   968 AA;  107752 MW;  A970B15B46D9BFCF CRC64;
     MAPFTDQEVV VLDDEEEIII IDDDDDDEDD EGDIEIIDFM PPPTGLSPED RFIGIRPYIP
     STPSIASVIS HPRSTSQGTQ LGGSCSPGTT RSRINSTFRR PNWGFNVSKS LSASRSSLGS
     CFQHRSESLG DPRSFVGCPS PRSGPGLFSG TAQEPIPLDD EEAVSEVTPR RISRAFEWRS
     RAVSLSSAPV ARPGIPSSSN FAILDDADPL GLVPVGDRLL SQEPGPEQAP THFKPGEIID
     LEEDVVEMLR VEDAYEEEEK RRRVRRKVEK VVHYERRNPT IVGAWQRIES TICLESITLK
     ANKTVQLKDE SFIRIKDILR NSETEEIRIR GHRLQRARDL NGLLQKKLNE LVVFLEVDLD
     DPRAPLEQST VEVSLEEVAR VRSVRFTNQK FPLARNVVLT EFRDKEHAAE DGGLTVRWTY
     TCTYESAGDR DHNVFKERSL ERLKVDECTP GFEISDEDAR TLWRGETIIG GSYRPGIDPE
     EVIEVPDSPS EVPIDVAGMQ EPEAVLCIPN QSIDIDEHDQ QTSELVPEGP EGVQGSREKR
     NHSAVDLEPA DVPTSGSALK RIRCQDLDEV EETREGVARM SLQTTEPEMP IDLEAQPELA
     DDQPLAPETI DLSIELPKMI DLVSSDPTPP EPDTPRPPPE PKPPVNRTAG QTYTYGDAFC
     GGGGSSRGAT MAGLRLRWGF DFNKHACLTW RTNFPFAHCH ELPAHEFVDL SKTDSNPDAM
     KVDILHLSPP CQFFSPAHTI EGTDDEMNTA SLFAVQEVIE VARARIVTLE QTFGIACSRF
     RFYFNALIQM FTTHDFSVRW AIVPLAQWGL PQRRQRLIII ASCPGEPLPL MPPPTHSATG
     PIPPLNLPPF VSANITLASI PYNASDHDIR SVIWDPERYQ TPWDGTKILP RAMTTSGGQN
     YHPSGKRDLT LREYASLQGF PPKHCFRGTY VKKQIGNAVP PVVAKVLFGH LKGSLEREDG
     VEGPELIE
//