ID K1WQS1_MARBU Unreviewed; 353 AA.
AC K1WQS1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=NADP-dependent leukotriene B4 12-hydroxydehydrogenase {ECO:0000313|EMBL:EKD14672.1};
GN ORFNames=MBM_07393 {ECO:0000313|EMBL:EKD14672.1};
OS Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Drepanopezizaceae; Drepanopeziza.
OX NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD14672.1, ECO:0000313|Proteomes:UP000006753};
RN [1] {ECO:0000313|EMBL:EKD14672.1, ECO:0000313|Proteomes:UP000006753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB_m1 {ECO:0000313|EMBL:EKD14672.1,
RC ECO:0000313|Proteomes:UP000006753};
RX PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA Huang M.-R., Wu R., Zhou Y.;
RT "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT evolution.";
RL BMC Genomics 13:382-382(2012).
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DR EMBL; JH921445; EKD14672.1; -; Genomic_DNA.
DR RefSeq; XP_007295282.1; XM_007295220.1.
DR AlphaFoldDB; K1WQS1; -.
DR GeneID; 18763328; -.
DR KEGG; mbe:MBM_07393; -.
DR eggNOG; KOG1196; Eukaryota.
DR HOGENOM; CLU_026673_29_2_1; -.
DR InParanoid; K1WQS1; -.
DR OMA; VRNTWMS; -.
DR OrthoDB; 179761at2759; -.
DR Proteomes; UP000006753; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205:SF19; PKS_ER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006753}.
FT DOMAIN 27..349
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 353 AA; 37713 MW; 24882437C315D906 CRC64;
MSSLTHTTKQ WILASKPTGA PVLSGPGATF KLQTTELPVL KDGQILCKVE YFSNDTGLRN
FIQSTVAPER FYVPTVPLGS PMRSGVIGTV LESLSPTYKV GDLVCNFHLG TWSERVILDA
ATCQPLPPLP NGLSVTHYLG AFGASGLAAY TGLYYAGEAK AGDTIVISAA AGATGIMAIQ
IAAKLLGAKR VIGIAGSEAK CKWVQELGAH ACVNYNSPTF EADLIAATPD EVDVYFDNVG
GHVLDVMLTR VKRHGTIAVC GAVSEYNTDE PMKLKNWFEL VSGRFTIRGF IMLDYMEKVP
MILGELIGAA ADGRIVLGAG ETIVEAKIEE QPQVWMRLFS GGNRGKLLTK LIS
//
