ID K1WWP4_MARBU Unreviewed; 517 AA.
AC K1WWP4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 28-JUN-2023, entry version 38.
DE RecName: Full=Pre-mRNA-splicing factor {ECO:0000256|RuleBase:RU369096};
GN ORFNames=MBM_08541 {ECO:0000313|EMBL:EKD13098.1};
OS Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Drepanopezizaceae; Drepanopeziza.
OX NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD13098.1, ECO:0000313|Proteomes:UP000006753};
RN [1] {ECO:0000313|EMBL:EKD13098.1, ECO:0000313|Proteomes:UP000006753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB_m1 {ECO:0000313|EMBL:EKD13098.1,
RC ECO:0000313|Proteomes:UP000006753};
RX PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA Huang M.-R., Wu R., Zhou Y.;
RT "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT evolution.";
RL BMC Genomics 13:382-382(2012).
CC -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC mRNA splicing. {ECO:0000256|RuleBase:RU369096}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369096}.
CC -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000256|ARBA:ARBA00008576,
CC ECO:0000256|RuleBase:RU369096}.
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DR EMBL; JH921451; EKD13098.1; -; Genomic_DNA.
DR RefSeq; XP_007296430.1; XM_007296368.1.
DR AlphaFoldDB; K1WWP4; -.
DR STRING; 1072389.K1WWP4; -.
DR GeneID; 18764476; -.
DR KEGG; mbe:MBM_08541; -.
DR eggNOG; ENOG502RZY8; Eukaryota.
DR HOGENOM; CLU_526830_0_0_1; -.
DR InParanoid; K1WWP4; -.
DR OrthoDB; 55448at2759; -.
DR Proteomes; UP000006753; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR InterPro; IPR045166; Spp2-like.
DR InterPro; IPR026822; Spp2/MOS2_G-patch.
DR PANTHER; PTHR15818; G PATCH AND KOW-CONTAINING; 1.
DR PANTHER; PTHR15818:SF2; G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN; 1.
DR Pfam; PF12656; G-patch_2; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU369096};
KW mRNA splicing {ECO:0000256|RuleBase:RU369096};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369096};
KW Reference proteome {ECO:0000313|Proteomes:UP000006753};
KW Spliceosome {ECO:0000256|RuleBase:RU369096}.
FT DOMAIN 210..264
FT /note="Spp2/MOS2 G-patch"
FT /evidence="ECO:0000259|Pfam:PF12656"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..82
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 55224 MW; C171470B27A54995 CRC64;
MGARERKRAV EGGARIERVS GFGVGGAERE GGGSGSGKGE RGPLVIPRMP NRDWRGGGVK
GSGKDLLPAE ERARREGRGL EAPGEGQGRG AVEGVDVVNG ADGGVRWGLT VTKKRHGDVR
AAEGSSVLPL GVAAGGNPDA DTDTDNGVEI KAEAAESSPQ PKSADEEALA SLLGTGTRPK
RPELVIQATG STMTELESYK AAVASAPPVS TIEDYERIPV EEFGAAMLRG MGWKGDGDSR
YGAGKKGKEV KRRQNLLGLG AKELQGAEEL GAWVQKSDVK RLKPGTAGGG GGSGGGRMKA
GDYKRERDRE RDRREERGGG SSYKRERERE RERERDGLGH RDPARYMHCA TQGSSIHPHR
AGRPPHTKLP HLFPSNYESK HWVYSSPSSQ GVRSIPCTVR ISARSASLSS KRMPSPTSPS
AVGKQALPER QCLAGKNVNL ALAAHPSGGR YPARDGIVRA VRPRRSERWR RWMQLRTPRT
ALATGRRLLR EEGKSAFCRQ AVCKPLGGLL SSARSGA
//
