ID K1Y2X7_MARBU Unreviewed; 1054 AA.
AC K1Y2X7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=EXS family protein {ECO:0000313|EMBL:EKD19509.1};
GN ORFNames=MBM_02746 {ECO:0000313|EMBL:EKD19509.1};
OS Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Drepanopezizaceae; Drepanopeziza.
OX NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD19509.1, ECO:0000313|Proteomes:UP000006753};
RN [1] {ECO:0000313|EMBL:EKD19509.1, ECO:0000313|Proteomes:UP000006753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB_m1 {ECO:0000313|EMBL:EKD19509.1,
RC ECO:0000313|Proteomes:UP000006753};
RX PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA Huang M.-R., Wu R., Zhou Y.;
RT "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT evolution.";
RL BMC Genomics 13:382-382(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR EMBL; JH921431; EKD19509.1; -; Genomic_DNA.
DR RefSeq; XP_007290635.1; XM_007290573.1.
DR AlphaFoldDB; K1Y2X7; -.
DR STRING; 1072389.K1Y2X7; -.
DR GeneID; 18758681; -.
DR KEGG; mbe:MBM_02746; -.
DR eggNOG; KOG1162; Eukaryota.
DR HOGENOM; CLU_006116_1_0_1; -.
DR InParanoid; K1Y2X7; -.
DR OMA; GDMYCSL; -.
DR OrthoDB; 7162at2759; -.
DR Proteomes; UP000006753; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006753};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 576..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..826
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 846..868
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..483
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 735..929
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 32..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 920..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1021
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1022..1037
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1054 AA; 119795 MW; F04D9968EF67AE17 CRC64;
MKFAKELEQD LVPEWRAKYL DYKVGKKYVK AVSRAQSRMN STPRTPAPQQ KPSLDPQNHS
LYGATSFQPR NHTSTSVRRF DGANEEATEG LRGSPAALGA DTQPDSENSD GRPSKPSRPT
PSVPIPAQNG GPSDQDVKYG SFVLTPPARP SASFELPDPA MEPAPVHDGS MSPRGVLSRI
PSNWSASNHS ALSRSAPSRP GPVAAPVSAY EVGRTLTPPH RSTFASIRNR AHRSGSVRPF
MRRVFSVGAS PDHAEGQRLD EDIAMDQVRS RQQEFFKFMD KELEKVETFY RAKEDEAGER
LKVLREQLHE MRNRRIDEVA QAQHAKVVRR AEESKMFDFG TKSSGQSKKD DDYRPTSRDG
LTAWLDPLER AYGNAKARIT GPRPGTNSKA LQNMNQSPEM RAKAQAERNE QADDGRDYIR
RPHYSDAVPY RTAKRKLKLA LQEHYRGMEL LKSYALLNRT AFRKINKKYD KAVDAHPPLR
FMSEKVNKAW FVNSDVLDSH LHAVEDLYAR YFERGNQKIA TGKLRSSTKG HADQSASAFR
NGVLIGIGAV FSIQGIIHGS ELLSDPDPVI RVQTSYLLQI YGGYFLALYL FSWFCLDCSI
WTRNKINYQF VFEFDTRHNL DWRQLSEFPS FLILVWGLFV WLNFTRYGAP AMFIYYPVVL
IFVTAVVILF PGPYIFHRSR KWFVYSHWRL LLAGLYPVEF RDFFLGDMYC SLTYFMSNIE
LFFCLYAHYW DNPAQCNSTH SRLLGFFSTL PGIWRALQCL RRYRDTRNVF PHLVNGGKYT
MTIVYCVSLS IYRIDRAKSN LAIFITFATI NAVYCSIWDL LMDWSLLQPD ASKPLLRDVR
GYKNPYYYYA AMFLDPIFRF NWIFYAIYTQ DLSHSTLVSF LVAFSEVTRR GVWVLFRVEN
EHCSNVARFK ASRDIPLPYS VSSDTEEDSV PTQQPPASLA EGRTSQTSPA VSRLRSHTSA
TLEAQATPGS SMRHRGLQRS FTAIMANAHT EDFEKRKTPG AGDSDNLVNR RRDGDDEDAH
AQGVDSSDED DEDDAQTILD AEVLLRQGAG GQRG
//
