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Database: UniProt
Entry: K2LNX0_9RHIZ
LinkDB: K2LNX0_9RHIZ
Original site: K2LNX0_9RHIZ 
ID   K2LNX0_9RHIZ            Unreviewed;       479 AA.
AC   K2LNX0;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   16-JAN-2019, entry version 42.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:EKF19459.1};
GN   ORFNames=NA2_08204 {ECO:0000313|EMBL:EKF19459.1};
OS   Nitratireductor pacificus pht-3B.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Nitratireductor.
OX   NCBI_TaxID=391937 {ECO:0000313|EMBL:EKF19459.1, ECO:0000313|Proteomes:UP000006786};
RN   [1] {ECO:0000313|EMBL:EKF19459.1, ECO:0000313|Proteomes:UP000006786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=pht-3B {ECO:0000313|Proteomes:UP000006786};
RX   PubMed=23209217; DOI=10.1128/JB.01905-12;
RA   Lai Q., Li G., Shao Z.;
RT   "Genome Sequence of Nitratireductor pacificus Type Strain pht-3B.";
RL   J. Bacteriol. 194:6958-6958(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EKF19459.1}.
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DR   EMBL; AMRM01000007; EKF19459.1; -; Genomic_DNA.
DR   EnsemblBacteria; EKF19459; EKF19459; NA2_08204.
DR   PATRIC; fig|391937.3.peg.1686; -.
DR   Proteomes; UP000006786; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006786};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006786}.
FT   DOMAIN      170    297       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      385    454       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     178    185       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   479 AA;  53596 MW;  89DFE11148A9E6D6 CRC64;
     MVFERVKAQL KARLGSEVYS SWFGRMKLME ASKSGVRISV PTAFLRSWIN GHYLDLITEL
     WKQEEPDTLK VEIVVRTATR NVRMPQEPKP AVARKVASRP QTALATGTLS SSHGPRGGVV
     QNAEAEGRSN ILGSPLDSRY TFESLIEGPS NRVACAAART VAESDSNAIR FNPLFLHASV
     GLGKTHMLQA IAAESLRRKP QARVVYLTAE YFMWRFATAI RDNNALTLKE QLRDIDLLII
     DDMQFLQGKS IQNEFCHLLN MLLDSARQVV VAADRPPSEL ESLEPRVKSR LNGGVSLEIG
     APDFGMRLAI LKQRLASAQA EDASLDIPEE ILVHVARSVT GSGRELEGAF NQLLFRQSFE
     PQITIDRIDE ILGHVCRAGE PKRVRIEDIQ RIVARHYNVS KTELLSNRRT RTIVKPRQVA
     MYLSKVMTPR SLPEIGRRFG GRDHTTVLHA VRKIEGLTDG DKQLAQEIEL LKRLISDQA
//
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