ID K2MQQ6_TRYCR Unreviewed; 511 AA.
AC K2MQQ6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF29440.1};
DE Flags: Fragment;
GN ORFNames=MOQ_006777 {ECO:0000313|EMBL:EKF29440.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF29440.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF29440.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF29440.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF29440.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHKC01013210; EKF29440.1; -; Genomic_DNA.
DR AlphaFoldDB; K2MQQ6; -.
DR EnsemblProtists; EKF29440; EKF29440; MOQ_006777.
DR OrthoDB; 5613985at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13859; BNR_3; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 2..223
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EKF29440.1"
SQ SEQUENCE 511 AA; 55624 MW; 03D816DF2121403A CRC64;
IHWRTTDGIP CMFTVEHHSS FRGLIGGGGS GIKMQDGTLA FPVEGTKKEK DGKTVSLVLY
LQGTETWTLS KGMSDDGCSD PSVVEREKDK LMMMTACDDG RRRVYESGDK GESWTEALGT
LSRVWGKKRD REAKKVGSGF ITATLGDVET EKRNVMLVTL PVYSTENDKK KGKLHLWLTD
NTHIVDIGPV SGDDDAASAL LYKSAESKTN EKEKEDKLIA LYEKKNVGEN KPSPGMVSVV
LTEELKRVKE VLATWKKVDE RVSQLCPSSI AAQETSTANA CGTVNITAGL VGFLSGNLSD
GIWRDEYLGV NATVKGAATA AKGTENGVTF TGRGAGAEWP VGRQGENQLY HFANYNFTLV
ATVSIHGEPK EENPIPFIGV KVNDDNKNPV LLGLSYNKEE KRAVLCSGGT TTEHSVAWEP
ETTHQVAIVL QNGTQGSVYV DGQRVGGSPS DLKDKDSKEI SHFFIGWEGS NEVEKVSQED
VSVTVRNVLL YNRPFNDNEI TALKANKVTV P
//
