ID K2MV94_TRYCR Unreviewed; 594 AA.
AC K2MV94;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF26346.1};
DE Flags: Fragment;
GN ORFNames=MOQ_009965 {ECO:0000313|EMBL:EKF26346.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF26346.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF26346.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF26346.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF26346.1}.
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DR EMBL; AHKC01021097; EKF26346.1; -; Genomic_DNA.
DR AlphaFoldDB; K2MV94; -.
DR EnsemblProtists; EKF26346; EKF26346; MOQ_009965.
DR OrthoDB; 138574at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR Pfam; PF13859; BNR_3; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007350}.
FT DOMAIN 103..430
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 594
FT /evidence="ECO:0000313|EMBL:EKF26346.1"
SQ SEQUENCE 594 AA; 63677 MW; 68C5290C85C9A681 CRC64;
MLPRVAAVTA PRTDNRRRVT GSSGRRREGS ESERQRLNMS RRVSTSAVLL LLLVMMCCVC
EAASADGSSG EGNAVDPFHG TTPAPYKWQE LTGPEAAGGS LRVPGLAEVI GSTFAVAEAQ
CTEGDGACSH TAIASTYIEA GGGGSKTISA MNDDVFLVEL VDAASGASKT RKTMQPTTIV
SGDSIYMLLG DYEGTTSGGQ AADEDGWRLL LTRGTLTEDG GQKRILWGEI CSVDPVAVGL
TKLLKRVIGG GGSGVVTTNG CLVLPMQALD KEGKSVVLSM RFNLLTEAWE LSSGATGNDC
KEPSIANFGG NLILITSCAA GYYEVFRSID SGRSWEESGR PITRVWGNSY GRTGYGVRCG
LTTVTIEGRE ALLVTTPVYS EEQKDRGRLH LWVTDGGRVH DAGPISDATD DAAASSLLYS
SGNDLISLYE NKSEGPYDLV AVHVTTQQEG IKSVVKWWQE LDEALRTCRP TATIDPVRRG
MCRHSILTDG LVGYLSGRST RSEWMDEYLC VNATVHGTVS GFSNGMTFEG PGAGAGWPVA
RSGQNQPYRF VHNRFTLVLM VVIHEKPQKR TPLPLIRVVM DNRVQTVLFG VFYT
//
