ID K2MWJ5_TRYCR Unreviewed; 359 AA.
AC K2MWJ5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=MOQ_006118 {ECO:0000313|EMBL:EKF30079.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF30079.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF30079.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF30079.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF30079.1}.
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DR EMBL; AHKC01012468; EKF30079.1; -; Genomic_DNA.
DR AlphaFoldDB; K2MWJ5; -.
DR EnsemblProtists; EKF30079; EKF30079; MOQ_006118.
DR OrthoDB; 56553at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd20071; SET_SMYD; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46402:SF2; HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5; 1.
DR PANTHER; PTHR46402; SET AND MYND DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 6..306
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 359 AA; 41721 MW; F8C25B508B7CEE84 CRC64;
MKLPYAKLET HYRPVRCVHA EYGCTMLFCS VRCRQAGWSR FHFAGCPGTM TDDQRNAYDE
FIHHDWEYRG VNYSDTVFLA FRFVCMAVTN IRLHRQSLEL AYKPIAQLIK APLSLFRFTY
LFYKEEADST KKKQRGEKHI EKVRLIRWEA FRKFRATHMS MTENDTTDEF LATGMTLLGR
ILRLTQEERS LFTVRRWSEL LGAVLLNGQE RSPPSNYDRL KEIVQRLPCG ESTMDAFEKE
VQKAGNEVQL LLQSSRGQGV YTVGCLFNHS CEPNLQVVYS ESGDETLSVV ALRDIEPGEE
LCISYIDESL SYPERQQELY EHYLFVCHCP KCEREAAAWE PIEPPEEALS SACTFSQLY
//
