ID   K2N0U3_TRYCR            Unreviewed;       257 AA.
AC   K2N0U3;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   03-MAY-2023, entry version 25.
DE   SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF28196.1};
DE   Flags: Fragment;
GN   ORFNames=MOQ_008065 {ECO:0000313|EMBL:EKF28196.1};
OS   Trypanosoma cruzi marinkellei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF28196.1, ECO:0000313|Proteomes:UP000007350};
RN   [1] {ECO:0000313|EMBL:EKF28196.1, ECO:0000313|Proteomes:UP000007350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|EMBL:EKF28196.1,
RC   ECO:0000313|Proteomes:UP000007350};
RX   PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA   Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA   Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA   Andersson B.;
RT   "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT   with the bat-restricted subspecies T. cruzi marinkellei.";
RL   BMC Genomics 13:531-531(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKF28196.1}.
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DR   EMBL; AHKC01016478; EKF28196.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2N0U3; -.
DR   EnsemblProtists; EKF28196; EKF28196; MOQ_008065.
DR   OrthoDB; 132570at2759; -.
DR   Proteomes; UP000007350; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR036278; Sialidase_sf.
DR   Pfam; PF13859; BNR_3; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        43..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          108..253
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         257
FT                   /evidence="ECO:0000313|EMBL:EKF28196.1"
SQ   SEQUENCE   257 AA;  27311 MW;  6253020A48DE7832 CRC64;
     MHSRVAAVKA PRTHNRRCVT GSSGRRREGG ESERQRPNMS RRVFASVVLF IVVVMMCCGT
     GGAADAVASK SVDEQSLQRI DLFVPNQTLV LPKKGTASET KSDSFVSPSL VSAGGVIAAF
     AEGHINAQYT ADGNLSKPIS SDVVAGYLDA KWNWSALVGK VNSSTWKAHS VLSTTDATNN
     NLVGVFYNPT TTTKGNKVFL LAGSLGELKG SGEQRKRENL GLKLVVGDVR EPTGSESTVR
     IDWAAPTSLL NESTKTA
//