ID K2N2T2_TRYCR Unreviewed; 344 AA.
AC K2N2T2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF28886.1};
DE Flags: Fragment;
GN ORFNames=MOQ_007349 {ECO:0000313|EMBL:EKF28886.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF28886.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF28886.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF28886.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF28886.1}.
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DR EMBL; AHKC01014577; EKF28886.1; -; Genomic_DNA.
DR AlphaFoldDB; K2N2T2; -.
DR EnsemblProtists; EKF28886; EKF28886; MOQ_007349.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13859; BNR_3; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..344
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003864148"
FT DOMAIN 73..328
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT NON_TER 344
FT /evidence="ECO:0000313|EMBL:EKF28886.1"
SQ SEQUENCE 344 AA; 37212 MW; 8451830864A9EE42 CRC64;
MSRHLFYSSV LLLVVAMMCC GTCGAAAAEG NDGKSDLRNF QKQQRVDLFV PRTTPVLLKD
KTSSEMRFSF VSPSLVSAAG VIAAFAEGHM KAKNLTDAQS LEPIPSDVVA GYIDSSWDWT
TLVDKVNQST WKAHTVLSTA SGEERVSVVH HPTTTTKGNK VFLLAETPVW PRANQTLNGV
ELTLVVGTVT NSTGGEPSGR ISWENPKSLS SLKTSAASHE SKFERVFPSG GSGVLMEGGT
LVFPVFGYNG ENVDFSTIIY STDDGQTWML SNGTSPKECS NPRITEWEGS LLMLVDCKDG
QRVYESRDMG TTWTGTIGTL PGVWTKSKSI IWDVSLHVDS LITA
//
