ID K2NC95_TRYCR Unreviewed; 562 AA.
AC K2NC95;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Amino acid tansporter, putative {ECO:0000313|EMBL:EKF32486.1};
GN ORFNames=MOQ_003661 {ECO:0000313|EMBL:EKF32486.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF32486.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF32486.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF32486.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF32486.1}.
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DR EMBL; AHKC01009816; EKF32486.1; -; Genomic_DNA.
DR AlphaFoldDB; K2NC95; -.
DR EnsemblProtists; EKF32486; EKF32486; MOQ_003661.
DR OrthoDB; 3601817at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950:SF688; AA_TRANS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 185..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..528
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 61489 MW; 4A12BAADA484A799 CRC64;
MNVESPVRLQ RESARASVHE SHLPLSCASG LSTSSRWRSA LSLRSEGKQT PTLSECSRTL
TPVPATHRLD VVNVAILDSN PRTAILQRCG HRAAANYHTS SESVSNGVEA KKIDATYESD
EDIDIHSLGE RLTDVLESSL RGAASVSQRG DANNTLGRAA FHIFKGNVGA GVFLLSTYYK
DAGYGVGFLL VFLLGILMID CALALVRSKQ KIDLLIVRTY PAVVGHILGS TLMHFTNFSL
IFTQFGFCVV YIQYASSMFT ALLSATQFYQ LLVLLSVLMV TPMSLFSHHM GMLAYASMIA
AVFVTLVLAG AVGEEVDYLS TRGVSQGTVF FEPTMRILVF ISGHMFSLEG IGVVLPVENS
MAAEDRPQFP TLVKYTLASI VTIYVVFGLL GYLAFGDALQ TSVVLAIPPS TTRTMLQVLL
GLSLIFSYPI QFLPAIQLVD RALGISVYKD PWNAYIVRAV LNIFFGALAA SIGADTINIF
ASFLGAFTGV HLMITMPVLL ALFTDHVLNC AQEDAEISFC DYIKFFFTMP DTIVECRWYL
YLFIAMLVWI GGTYYTFDSV FG
//
