ID K2NJU6_TRYCR Unreviewed; 392 AA.
AC K2NJU6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF29177.1};
GN ORFNames=MOQ_007052 {ECO:0000313|EMBL:EKF29177.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF29177.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF29177.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF29177.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF29177.1}.
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DR EMBL; AHKC01013901; EKF29177.1; -; Genomic_DNA.
DR AlphaFoldDB; K2NJU6; -.
DR EnsemblProtists; EKF29177; EKF29177; MOQ_007052.
DR OrthoDB; 3887240at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13859; BNR_3; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 87..389
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 42271 MW; 7E20B93B19BDECBE CRC64;
MHSRVAAVMA PRTHNRRRVI GSSGRRREGR ESERQRPNMS RHLFYSPVLL LLLVMMCCNT
GGAAEGEANI KWRGVTDNEG KVDALGAPGL LKVGNDVFAV AEAQCKKGGD ANIFTGIASQ
RLTTQTANVP MEVLKEVKKT QVLEKSSSAA DKIDVSRPTT VVEGNDIYML VGKKIWTTAT
DPEESGADEW WLLLVKGNVT EGSGGEKAIH WKDTTDVPRI SIGQHNHSLT GLIGSGGSGV
KTNDGKLVFP VEAVKGSNSR EEVGKTASLI LYTSKDTKRW TLSNGTSADG CSDPSVVEWK
DNQLMMMTAC DDGRRRVYES GDKGESWTEA LGTLSRVWGN KQGGEAKAVG SGFITATIGN
GEDNKRKVML VTLPVYSSKN GEINEKGVLI FG
//
