ID K2NJY1_TRYCR Unreviewed; 678 AA.
AC K2NJY1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Carnitine O-palmitoyltransferase II, putative {ECO:0000313|EMBL:EKF39740.1};
GN ORFNames=MOQ_000030 {ECO:0000313|EMBL:EKF39740.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF39740.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF39740.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF39740.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF39740.1}.
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DR EMBL; AHKC01000138; EKF39740.1; -; Genomic_DNA.
DR AlphaFoldDB; K2NJY1; -.
DR EnsemblProtists; EKF39740; EKF39740; MOQ_000030.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF16; CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 62..660
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 391
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 678 AA; 77029 MW; 8709CA4054A5C8E1 CRC64;
MLRRSFVLCI ATAPIVVPKD IHDWSRLRQY LEDFTVGACT DTGVLDASII PTRHLQRSLF
RLPIPKLKNT CSRYLDAVKP LVPPKQFDAT SKIVKDFESG EGLSLHEELV RTDKANKHTS
YISADWFDLY LLDRKPLPVN TNPCLITRRD QDKGDMLTRA TFWITSSVAF YRMYLENTLK
PDIFNFGSRD HYSRKDWFER TVALSPRSIA AKVCVFGSNF HAFPLDMSQY TNLMNSTRIP
GLIKDEVRGF GFAPHIIVQF RGHQYVVTVA DSECRPLPEE QIYARLKAIT NLNPTPPKVD
IGVFTSTDRS TWHSVRTEML RDIENQKSFE LLDTAMFVLN LDDDVEVDFL TSRGAVETIR
VMLVKNVNRW WDKSLSVIVT KDGFLGVNFE HSWGDGVAVL RYTQDVFNHS IMRSCKSMRQ
DAAPTEGVRQ LKWRLTPKLE QEGVKAKTRI DADIRRMDFC SCLVNEIGSS DPVFRKGPIK
VDPFLQLAMQ LAWWRLYKST VSTYESASTA AYRHGRTECI RSATIESQAF TILMDNSNAT
TNEKFEALLK AAKKHLQISK NAKMGEGFDR HLFALQNVAL RRNPNCVPDL FLDSSYKTVG
SNLISTSTLR SDALVGGGFG PVSPGYGIGY GSERKCLCFN VSCWKEFGPR YSADEFTHAL
YSAVVDMYNI MLSVKKNE
//
