ID K2PXD0_9LACT Unreviewed; 577 AA.
AC K2PXD0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Lipid A export ATP-binding/permease protein MsbA {ECO:0000313|EMBL:EKF52071.1};
GN ORFNames=C426_0542 {ECO:0000313|EMBL:EKF52071.1};
OS Lactococcus garvieae DCC43.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=1231377 {ECO:0000313|EMBL:EKF52071.1, ECO:0000313|Proteomes:UP000006787};
RN [1] {ECO:0000313|EMBL:EKF52071.1, ECO:0000313|Proteomes:UP000006787}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCC43 {ECO:0000313|EMBL:EKF52071.1,
RC ECO:0000313|Proteomes:UP000006787};
RX PubMed=23209230; DOI=10.1128/JB.01864-12;
RA Gabrielsen C., Brede D.A., Hernandez P.E., Nes I.F., Diep D.B.;
RT "Genome Sequence of the Bacteriocin-Producing Strain Lactococcus garvieae
RT DCC43.";
RL J. Bacteriol. 194:6976-6977(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF52071.1}.
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DR EMBL; AMQS01000005; EKF52071.1; -; Genomic_DNA.
DR RefSeq; WP_003134815.1; NZ_AMQS01000005.1.
DR AlphaFoldDB; K2PXD0; -.
DR PATRIC; fig|1231377.3.peg.545; -.
DR eggNOG; COG1132; Bacteria.
DR Proteomes; UP000006787; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18548; ABC_6TM_Tm287_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF618; ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EKF52071.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..304
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 336..571
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 577 AA; 63535 MW; 51A231971A8CE421 CRC64;
MVMKAIGKYK LLVFAALATM LLQVGAALWQ PQYMKNILSV MAESISISDK VDKINHYGVY
LLIIAVVGLV GSILNTVTAA KLAQAVSADI REETFRKIQT FSYENIEKFN AGNLVVRMTN
DINQVQTLLM MTFQVLIRVP LLFVGAFILS IITMPELWWI IIVMVVLIVI VTMVSMKSMG
PHFMVFQKLM DRINGIAKEN LRGARVVKSF VQEKDQIQKF DETSDELLGH NMAVGYTFAA
MIPAFTIISQ LAVFGAILLV STYVTRDLNT AANTLGGIMS FIQYMMQIMM AIIMGGMMSM
FASRGFVSIG RINEVLKTEP AMTFEDVPDE ELNGSVKFDH VSFSYPNDEH PTLQDISFEI
KSGQMVGIVG ATGSGKSTLA QLIPRLFDPT EGTVSVGGKD LRHVSKATLK NTISIVLQKA
ILFSGTIAGN LKQGKSDATV EQMSRAAEIA QAAEFIEKLP DHYESQVEER GNNFSGGQKQ
RMSITRGIIK DPKVLILDDS TSALDAKSEK LVQEALSKDL KDTTTIIIAQ KISSVVHADN
ILVLDEGKLV AQGTHAELVE NSSVYREIYD TQKAKED
//
