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Database: UniProt
Entry: K2Q9S2_9RHIZ
LinkDB: K2Q9S2_9RHIZ
Original site: K2Q9S2_9RHIZ 
ID   K2Q9S2_9RHIZ            Unreviewed;       737 AA.
AC   K2Q9S2;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   08-MAY-2019, entry version 37.
DE   SubName: Full=Enoyl-CoA hydratase {ECO:0000313|EMBL:EKF57751.1};
GN   ORFNames=QWE_19688 {ECO:0000313|EMBL:EKF57751.1};
OS   Agrobacterium albertimagni AOL15.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
OX   NCBI_TaxID=1156935 {ECO:0000313|EMBL:EKF57751.1, ECO:0000313|Proteomes:UP000007123};
RN   [1] {ECO:0000313|EMBL:EKF57751.1, ECO:0000313|Proteomes:UP000007123}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AOL15 {ECO:0000313|EMBL:EKF57751.1,
RC   ECO:0000313|Proteomes:UP000007123};
RX   PubMed=23209236; DOI=10.1128/JB.01912-12;
RA   Trimble W.L., Phung le T., Meyer F., Gilbert J.A., Silver S.;
RT   "Draft Genome Sequence of Agrobacterium albertimagni Strain AOL15.";
RL   J. Bacteriol. 194:6986-6987(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EKF57751.1}.
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DR   EMBL; ALJF01000016; EKF57751.1; -; Genomic_DNA.
DR   RefSeq; WP_006727927.1; NZ_ALJF01000016.1.
DR   STRING; 1156935.QWE_19688; -.
DR   EnsemblBacteria; EKF57751; EKF57751; QWE_19688.
DR   PATRIC; fig|1156935.5.peg.4010; -.
DR   OrthoDB; 977512at2; -.
DR   BioCyc; AALB1156935:G1HB2-3954-MONOMER; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000007123; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007123};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296}.
FT   DOMAIN      328    507       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      509    606       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   737 AA;  79423 MW;  560D9A7F81841C91 CRC64;
     MTYKNFTIET DSDGIALVTW DMPDKSMNVF TVEVMDEIEK ILEQTVADDG IKGVVFTSGK
     SSFSGGADLT MIKGMFSMLE EEKAKDPAAA VQKLFDAAGR MTWLWRKIET NGKPWVSAIN
     GTCMGGATEL SLACHGRVAS NAKSVKIGLP EVKVGIFPGA GGTQRVARLA NTQDALQMMT
     TGQTLSAARA KAMNLVHQVV EPGELINAAK QMIKDGLKPV APWDEKGFKV PGGGIWTPAA
     AQLWPAASAI LRRETAGNYP AALAILKSVY EGLQVPFDTG LRIEQRYFTE IVQTTEAYSM
     IRSLFVSMQE LNKGARRPAG QPKSEIKKIG VVGAGFMGAS IAYVTAAAGI NVVLIDRDME
     AAGKGKTHSE GLVAGAVGKG KLTKDEGDRL LSLITPSDDY GTLADADLVI EAVFEDRDVK
     KAVIEKVEAV LPEGAIFASN TSTLPITGLA GNSKRPVDFI GIHFFSPVEK MMLTEVILGK
     ETGDKALAVA LDYVAAIKKT PIVVNDTRGF FVNRCVLRYM SESYNMLIEG VPPVMIENAA
     KFAGMPVGPL ALNDEVAIDL SYKILKATVA DLGEKAIDPR HMELVSRMVE KEERFGRKNG
     KGFYDYPAKP AKKHIWPGLK DLHPQLKPEA VNVKTLQERF LATIALEAAR TVEEGIVTDP
     READVGSILG FGFAPYTGGA LSYIDGMGVK TFVELCERLA KDYGAHFTPT PLLKEMAAKG
     ETFYGRFDPY GEAAKAA
//
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