ID K2R5K7_MACPH Unreviewed; 636 AA.
AC K2R5K7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE SubName: Full=Lecithin:cholesterol acyltransferase {ECO:0000313|EMBL:EKG17656.1};
GN ORFNames=MPH_05105 {ECO:0000313|EMBL:EKG17656.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG17656.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG17656.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG17656.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG17656.1}.
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DR EMBL; AHHD01000229; EKG17656.1; -; Genomic_DNA.
DR AlphaFoldDB; K2R5K7; -.
DR STRING; 1126212.K2R5K7; -.
DR VEuPathDB; FungiDB:MPH_05105; -.
DR eggNOG; KOG2369; Eukaryota.
DR HOGENOM; CLU_016065_1_0_1; -.
DR InParanoid; K2R5K7; -.
DR OrthoDB; 589269at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR PANTHER; PTHR11440:SF97; BCDNA.GH02384; 1.
DR PANTHER; PTHR11440; LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED; 1.
DR Pfam; PF02450; LCAT; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:EKG17656.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129};
KW Transferase {ECO:0000313|EMBL:EKG17656.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 70882 MW; FE4CDF428F405AAD CRC64;
MSFLRRRIAG DASGSSSEPS REPTPDPTQD EQYRVVTARK LHQLSVAKEK ARASARGSKR
WNLFVLGLGG VIGIVGAGWF AQNNDMIDLP AIADLNLDSI ADMLPAGLLQ DARDLQRHER
EAVAYDSFAV GLHARSQGIE ATHPVIMIPG VISTGLESWS TVEDSRQYFR KRLWGSWSMM
RALVMDKAGW KRHIMLDKTT GLDPPGGIKL RAAQGFDATD FFITGYWIWN KILENLATIG
YDPTNAFTAA YDWRLSYGNY EVRDQYFTRL KTHIETAVRI SNKKVVLLSH SMGSQVLYYF
FHWAEAEGYG NGGPGWVDAF VDSWINISGC MLGTPKGMPA VLSGEMKDTA QLNAFAVYGL
EKFLSRAERA EIFRAMPGIS SMLPMGGDAV WGNHTWAPDD TPDQMHTYGS FIKFRNSNSS
DTARNLTVSE ALPYLFNQSE EWYSTQVLSS YSYGLAHTRE EVEANQNIPS KWVNPLETRL
PLAPNLKIYC FYGVGKPTER AYFYHEDNDP LSSVNVTVDT TYTEGEADHG IVMGEGDGTV
NILSSGYMCT KGWKMKRYNP AGVKIKTYEM PHEPDRFSPR GGPNTGDHVD ILGRSSLNDL
ILKVAGGKGD LIEENIVSNI LEYADKVQIW DDDEGN
//
