ID K2RFN7_MACPH Unreviewed; 1048 AA.
AC K2RFN7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 22-FEB-2023, entry version 39.
DE SubName: Full=I/LWEQ domain-containing protein {ECO:0000313|EMBL:EKG11692.1};
GN ORFNames=MPH_11185 {ECO:0000313|EMBL:EKG11692.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG11692.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG11692.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG11692.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG11692.1}.
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DR EMBL; AHHD01000467; EKG11692.1; -; Genomic_DNA.
DR AlphaFoldDB; K2RFN7; -.
DR STRING; 1126212.K2RFN7; -.
DR VEuPathDB; FungiDB:MPH_11185; -.
DR eggNOG; KOG0980; Eukaryota.
DR HOGENOM; CLU_004601_0_0_1; -.
DR InParanoid; K2RFN7; -.
DR OrthoDB; 7775at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd17007; ANTH_N_Sla2p; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF15; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR Pfam; PF07651; ANTH; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 8..138
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT DOMAIN 805..1048
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT REGION 267..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1007..1043
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 269..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 119082 MW; B9EE9ED535290CF1 CRC64;
MYGSRNVDMG KQESELAINI RKATSIDETA PKRKHVRAAI VYTWDHKNSD SFWAGMKVQP
ILADEVQTFK ALITIHKVLQ EGHPIVLKQA QAHIGFLESL QRGVAGGEGM RGYAPLISEY
VYYLMAKLAF HRQHPEFNGT FEYEEYISLK SINDPNEGYE TISDLMTLQD QIDSFQKLIF
SHFRNGTNNE CRISALVPLV QESYGIYKFI TSMLRAMHTT LGDDEALAPL RGRYDAQHYR
LVKFYYECSN LRYLTSLITV PKLPQDPPNL LSEDEDRPAL PARPKKDDDT PKRAASVDPE
PINEFWKNEQ KRQQEEYEAE QKRLAQQWEE AQRRQQEEQM RAQREFEEQQ RLAAEQARMA
QEQLAREQFA QQTQGRMAEL ERENLAARNQ YQQDQLLLQQ YDARVKALEN ELQSIQGNFA
QQSQSKDDQI RALQEQLNTW RSKYEALAKL YSQLRHEHLE LLQKFKSVQL KAASAQEAID
QREKLQRELK TKNLELADMI RERDRALHEK DRTTGGHKDE VEKLQRELRL ALDRADQADR
NKGSELSAML SRHNREIADL EEALRNKNRQ LEDLQLRFRE GDSELERQLR EKEDELEIFK
AGMDQTLLEL NELKMNQQAS NNASDEVFDT VILDNLRKIG DIIDSVLQSG VQRVDDALYE
LDSSMQAGNQ NASGAYVLSQ IEKASSCAME FSTAYNNFIA DGPNATHAEI IRTVNAFAGS
IADVLSNTKG LTRFASDEKK GDQLIGAARH SAESTVNFFR SLQSFRLEGM EDLQKTDVVL
NCNSEVQLNL QKLSKLADAF APKSKISANQ GDLGDLVDRE MANAANAILA ATERLSKLKD
RSRDSYSTYE LRIHDAILGA AIEVTNAIAR LIKAATESQQ EIVREGKGTS SRTAFYKKNN
RWTEGLISAA KAVANSTNLL IETADGVISG RNSPEQLIVA SNDVAASTAQ LVAASRVKAS
FMSKTQDRLE AASKAVTQAC RALVRQVQSI INERNRDGEE AVDYSKLSGH EFKVREMEQQ
VEILQLENAL SAARHRLGEM RKLSYQEE
//
