ID K2RNX7_MACPH Unreviewed; 1091 AA.
AC K2RNX7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Translation elongation factor EFG/EF2 {ECO:0000313|EMBL:EKG16438.1};
GN ORFNames=MPH_06348 {ECO:0000313|EMBL:EKG16438.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG16438.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG16438.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG16438.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG16438.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHHD01000268; EKG16438.1; -; Genomic_DNA.
DR AlphaFoldDB; K2RNX7; -.
DR STRING; 1126212.K2RNX7; -.
DR VEuPathDB; FungiDB:MPH_06348; -.
DR eggNOG; KOG0467; Eukaryota.
DR HOGENOM; CLU_002794_3_1_1; -.
DR InParanoid; K2RNX7; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EKG16438.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:EKG16438.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 17..280
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 212..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1091 AA; 119348 MW; 7808DAA3BA3F4587 CRC64;
MPVVSPEKLV ELQQAHDDIR NICILAHVDH GKTSLTDALI ATNGIISPKL AGKIRYLDSR
PDEQLRGITM ESSAISLYFS LMRRSSPDAE PVRQESLINL IDSPGHIDFS SEVSTASRLC
DGAVVLVDAV EGVCSQTVTV LRQTWVEKIK PLLVINKMDR LITELKMSPG EAYTHLSKLL
EQVNAVMGSF FQGERMEDDL KWREKMDERI SAKAKDRAET DGSEVPTEAT ADYEEKDDED
IYFAPEKNNV IFSSAVDGWA FTVKQFAALY ERKLGIKRSV LEKVLWGDYY LDPKTKKVLG
SKHLKGRALK PIFVQLVLEQ VWAVYEATTG GNKGKGDPAL VEKITKGLNL TLPTHLLRSR
DPRTLLMAIF AAWLPLSTAV LVSVIESLPS PPAAQAARMK ELVEQSPGAD HVDPKVKDAM
AGFKKEKEAP VVAYVSKMVS VPESELPENK RRGGGTLSAE EARELARKKR AEFARAQALQ
NGGDDDDVAG MTQALGATSV ISDEGPQDAD EDGESQQKAD PEHLIGFARI YSGTLSVGDE
VYVLPPKFSP AAPHAHPQPQ KVTITALYLL MGRGLEPLTT VPAGCVFGIG GLAGHILKSG
TICSQLEGSV NLAGVNLGSQ PIVRVALEPE NPGDLAKMVA GLKLLVQSDP CVQYELLESG
EHVILTAGEL HLERCLKDLR ERFARCEIQA GAPIVPYRES IVAAAEMNPP QNKDLPRGTV
VAVTTSKHVT VRLRVRPLPA PVTEFLTKNA GAIKRLYAER RAAEEEKRGA ADGAGEGQGE
EGVGEEKEGL VADVDLTEAG QVLTIKEFRK QLITAFAETK GEKEVWEGVA EKISAFGPRR
TGPNLLVDET GLRVLPHILS LDPEQHTAAQ PQSDEALTPH DFSDKITYAF QLATYQGPLC
NEPVQGISVH VESVELDQSA ADRTALGRLT GEVIKATRSG IHAGFLDWSP RMLLAMYSCE
IQCSTEVLGR VYGVVTRRRG RIVSEAMKEG TPFFSITALL PVAESFGFSE EMRKRTSGAA
QPQLVFVGFE MLDEDPFWVP WTEEEIEDLG ELADKENVAK RYMDGVRKRK GLFVGEKIVR
DAEKQKTLKS K
//
