ID K2RX08_MACPH Unreviewed; 454 AA.
AC K2RX08;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|PROSITE:PS50879};
GN ORFNames=MPH_14085 {ECO:0000313|EMBL:EKG08960.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG08960.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG08960.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG08960.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG08960.1}.
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DR EMBL; AHHD01000893; EKG08960.1; -; Genomic_DNA.
DR AlphaFoldDB; K2RX08; -.
DR VEuPathDB; FungiDB:MPH_14085; -.
DR eggNOG; ENOG502SNYY; Eukaryota.
DR HOGENOM; CLU_000680_26_0_1; -.
DR InParanoid; K2RX08; -.
DR OrthoDB; 1905142at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 167..301
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 133..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 50742 MW; 37A405A3D985F71D CRC64;
MLPVATYGAE VWYEGTMKPI PYTARTVIPR QSYHTATIDR ALRTAARAVV PVWRTTPIPV
LHRETGIPPA SVLLQQIQRR ASLRLRLLDE AHPIVGRTQV IRGHGGWAPR APNSPPRATR
LQRTAQLVED CERPQLLQPS YTNSPQKTVQ GKERGTKEFA ESLKRDPPET LHIYSDGSSM
NSKTAWAFVA YSHGARIHAQ SGSLHKAEVF DAEIRGAAEG LAWAAANAEA LQATNVTLCI
DNTSVIQGID GHTPASSQSQ FTRLKSTRQE LPIPVETRWC PGHMGITGNE EADQLAKAAI
GLQNDEQGPA SVSWTRRRNR EERSRIYEAW WEEHQTPTYQ HLGLKIRKGR NPELALPRQT
LYRLIAERTG HGDFAEYHRR AKHERAELTC KCGAEKAQWH FIDCRLAAGW EYPGTATRAE
KIRNLLGPTG WFLFQNLLES TAVFRGGCQG TVNG
//
