ID K2S0D1_MACPH Unreviewed; 936 AA.
AC K2S0D1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Dynamin-type G domain-containing protein {ECO:0000259|PROSITE:PS51718};
GN ORFNames=MPH_02269 {ECO:0000313|EMBL:EKG20423.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG20423.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG20423.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG20423.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001270};
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004374}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG20423.1}.
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DR EMBL; AHHD01000087; EKG20423.1; -; Genomic_DNA.
DR AlphaFoldDB; K2S0D1; -.
DR STRING; 1126212.K2S0D1; -.
DR VEuPathDB; FungiDB:MPH_02269; -.
DR eggNOG; KOG0448; Eukaryota.
DR HOGENOM; CLU_011752_0_0_1; -.
DR InParanoid; K2S0D1; -.
DR OrthoDB; 1381184at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027094; Mitofusin_fam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10465; TRANSMEMBRANE GTPASE FZO1; 1.
DR PANTHER; PTHR10465:SF0; TRANSMEMBRANE GTPASE MARF-RELATED; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 283..577
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 615..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 103278 MW; 88930F9CEC36FE1D CRC64;
MDPNKPSGSG YASPSGNSHG RHPESYLSPT ASRRPSYMTV GTGSVSESAS RLAAMLDDDS
GYGGSIADTS SARSGWHPGI TEDRPTPSHT PVLPGESNPA SEHERRTLAS HIHQLYYNQN
RTALGRSIGR TVETLKKLQQ MNLQWPAHYP QVQRADTPAP ISGQNEPRPG LQHTQSTWDN
HSGVEQDTPS RPKPLRRAGT SLGEDTTMAE SSSAATQRSA PEPRLVTPQL AQEFSVLKID
LKMGALSQTE LVHSLEKGAI AQLLDNQISK SIRHLYSLRE RIEDTSSKVL VTGDLNAGKS
TFCNALLRRK ILPEDQQPCT SIFCEVLDSR ENGGLEEVHA IPIGSVYNRD NEATYDVYTL
KQLEDIVTEN ERYASCKVYV KDIRTVDESL LNNGVVDIAL IDAPGLNADS LKTTAVFARQ
EEIDVVVFVV SAANHFTLSA KEFIFNAARE KAYMFMVVNG FDNIRDKKRC QDQILKQVGK
MSPATYKEAS ELVHFVTSRS IPVAPLEVTN GGGGSGSGSG DGGPGGDPDD DDDDNGDFGS
SDKGKGKEKE RLRDFEELEG ALRRFVLEKR ARSKLAPAKT YLMNVLADLN NLATVNRDVA
QSELDRVTSE LKQLEPEYEK SKKSRAEASE DADHTIEETA ADVYEYTRDT VTTTISRVAE
HDLGLEYPGL FNAFQYAEDI KAAMIQEIAE SVYNCEDYAR DKTEIGFRRI SSLGILHLDN
DWPQLTFHSE KMFRKRRDAL SRQVDFDVEV WDFFDLAGLW ERQEKVAGTS MAVTVAGVVG
TRMVGGVSWV DGAMGAMRIM GSNNLRRMIV PSLILAVGLG ISYALQSIPK SLPRRLSTKL
SAQLDLLDYT HANASRISSE ARKALKHPAQ ELRVGLERSV EKLQVKREKA TEFKRESEVA
RKYFGNLVRE SHDIRHSVER VDLEGPAPGV AAAYEG
//
