ID K2S9K6_MACPH Unreviewed; 498 AA.
AC K2S9K6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Fatty acid desaturase type 1 {ECO:0000313|EMBL:EKG13570.1};
GN ORFNames=MPH_09286 {ECO:0000313|EMBL:EKG13570.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG13570.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG13570.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG13570.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG13570.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHHD01000407; EKG13570.1; -; Genomic_DNA.
DR AlphaFoldDB; K2S9K6; -.
DR STRING; 1126212.K2S9K6; -.
DR VEuPathDB; FungiDB:MPH_09286; -.
DR eggNOG; KOG4232; Eukaryota.
DR HOGENOM; CLU_016265_3_0_1; -.
DR InParanoid; K2S9K6; -.
DR OrthoDB; 294339at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03506; Delta6-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR19353:SF30; DELTA 8-(E)-SPHINGOLIPID DESATURASE; 1.
DR PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR Pfam; PF00487; FA_desaturase; 1.
DR PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 214..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 187..458
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 56490 MW; 3917B9A738C3FC3A CRC64;
MKAYRIGRVQ QPWTNLEPPI RAGPHRKTPE HESDGDDSAS SASNHDASSI FSAKPDPLSS
SNSSVGASDS EPDAAKSSEC RRRIAAKPTA PAAGATASKL AAEGLSRAVY TAALEQQEIA
DGIRSYPSLD PETQQAIRTD YDALHKLIQE KGYYNCPYLE YGKEMIRYAI LFGFFVYFLR
KEWYMTSAAF LGMFWQQIMF TAHDAGHRGI TGDFVVDTVI GAFIADFCCG LSIGWWKSSH
NVHHLVTNMP EHDPDIQNIP LFSTSPTYFK SIRSTFYDFT FYWDKAADLL VPYQKYTYYP
VMAIARFNLY LLSWLHLLSP RAAQLGSAWW TRYLELVFMT CYWAIFGYAL LLRTLPDWPT
RVAFVLVSHM ITMVLHVQIT LSHWGMPTSD LGPTESFPQR QLRTTMDVDC PEWLDFLHGG
LQFQAVHHLF PRVPRHNLRK CQALVRDFCT KTGIKYQCQG FVDGNKVVLT RLEEVAKMVE
TLVQCQLHMA ETGESGLH
//
