ID K2SBL5_MACPH Unreviewed; 840 AA.
AC K2SBL5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
GN ORFNames=MPH_08550 {ECO:0000313|EMBL:EKG14260.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG14260.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG14260.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG14260.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG14260.1}.
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DR EMBL; AHHD01000362; EKG14260.1; -; Genomic_DNA.
DR AlphaFoldDB; K2SBL5; -.
DR STRING; 1126212.K2SBL5; -.
DR VEuPathDB; FungiDB:MPH_08550; -.
DR eggNOG; KOG0469; Eukaryota.
DR HOGENOM; CLU_002794_11_2_1; -.
DR InParanoid; K2SBL5; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR CDD; cd03700; EF2_snRNP_like_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EKG14260.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 17..254
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 840 AA; 93572 MW; 51B2FBE9DFFB755A CRC64;
MVNFTVEEIR GLMDNPVNIR NMSVIAHVDH GKSTLTDSLV QRAGIISAAK AGEARFTDTR
PDEQERGVTI KSTAISLYAQ LIDPEDLKDI PVKTEKNDFL INLIDSPGHV DFSSEVTAAL
RVTDGALVVV DTVEGVCVQT ETVLRQALGE RIKPVVIINK VDRALLELQV SKEDLYQNFS
RVIESVNVVI ATYFDKVLGD VQVYPDKGTV AFGSGLHGWA FTVRQFASRY SKKFGVDKNK
MMERLWGDNY FNPKTKKWTK TAPENGERAF NQFILDPIFR IFNAVMNFKK EEIPTLLEKL
EIKLTSEERD LEGKQLLKVV MRKFLPAADA LLEMMILHLP SPATAQKYRM ETLYEGPHDD
ESAIGIRDCD PKGPLMLYVS KMVPTSDKGR FYAFGRVFSG TVRSGLKVRI QGPNYTPGKK
EDLFVKSIQR TILMMGRFVE PIEDVPAGNI LGLVGIDQFL LKSGTLTTSE TAHNMKVMKF
SVSPVVQRSV EVKNANDLPK LVEGLKRLSK SDPCVLTYIS ESGEHVVAGA GELHLEICLK
DLEEDHAGVP LRISDPVVQY RETVGGESRM TALSKSPNKH NRLYVTAAPL GEEVSKDIEQ
GKIGPRDDFK ARARLLADEH GWDVTDARKI WCFGPDTNGA NLLVDQTKAV QYLNEIKDSV
VSGFQWATKE GPIAEEPMRS IRFNIMDVTL HADAIHRGGG QIIPTARRVL YAATLLAEPA
LLEPVFLVEI QVPENAMGGI YGVLTRRRGH VFEEAQRPGT PLFNVKAYLP VKESFGFNAD
LRSNTSGQAF PQSVFDHWQI LPGGSPIDKT TLPGQVVEDM RKRKGLKPEV PGYENYYDKL
//
