ID K3UPT3_FUSPC Unreviewed; 584 AA.
AC K3UPT3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=FPSE_05618 {ECO:0000313|EMBL:EKJ74321.1};
OS Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ74321.1, ECO:0000313|Proteomes:UP000007978};
RN [1] {ECO:0000313|EMBL:EKJ74321.1, ECO:0000313|Proteomes:UP000007978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS3096 {ECO:0000313|EMBL:EKJ74321.1,
RC ECO:0000313|Proteomes:UP000007978};
RX PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT "Comparative pathogenomics reveals horizontally acquired novel virulence
RT genes in fungi infecting cereal hosts.";
RL PLoS Pathog. 8:E1002952-E1002952(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ74321.1}.
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DR EMBL; AFNW01000113; EKJ74321.1; -; Genomic_DNA.
DR RefSeq; XP_009257011.1; XM_009258736.1.
DR AlphaFoldDB; K3UPT3; -.
DR EnsemblFungi; EKJ74321; EKJ74321; FPSE_05618.
DR GeneID; 20364236; -.
DR KEGG; fpu:FPSE_05618; -.
DR eggNOG; ENOG502QQ5E; Eukaryota.
DR HOGENOM; CLU_024508_3_2_1; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000007978; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007978};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 536..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 584 AA; 62519 MW; 2F62AF8EBA569FA3 CRC64;
MGWMENANHK IAASAVGRWF QLDGSGHPRE RKGSLFFTEI RAGLATFFAM AYIIAVNSSI
VSESGGTCVC PAYKDGACVP DDAYQLCVAE VKRDAVTATA AISALATFFM GLFANLPVGL
APGMGLNAYF TYTVVGPGGS GPVPYELALT AIFIEGFIFF GLALFGMRQW LARAIPRCIK
LATSVGIGLF LTLIGLTYSE GIGLIVGSTS TPLELAGCEA SYRDPATGLC PSSQKMRNPS
MWIGIFCGGI LTVLLMMYRV KGAVIAGILL VSIISWPRGT DVTYFPYDTL GDDRFDFFKK
VVDFHQIKRT LNVLQFDISG HSGQFGLALI TFLYVDILDC TGTLYGMARF ADLVDPVTQD
FEGSSIAYMV DALSISIGAV LGVPPVTAFV ESGAGISEGG KTGITAMVAG ICFFISIFFA
PIFASIPPWA TGCVLILVGS MMVGAVTEIN WKYMGDAVPA FLTIAIMPFA YSIADGLIAG
ICTYMVLNTV VLLVKVISGG RIVPPNYEER DGWTWRIPGG FLPPWMNRLA HGKKDFWRED
NPPHNTNNET VVSDTAAPKE NGSDHGGSEG GKVAETTLPR EKET
//
