ID K3V7H0_FUSPC Unreviewed; 506 AA.
AC K3V7H0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKJ69139.1};
GN ORFNames=FPSE_10683 {ECO:0000313|EMBL:EKJ69139.1};
OS Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ69139.1, ECO:0000313|Proteomes:UP000007978};
RN [1] {ECO:0000313|EMBL:EKJ69139.1, ECO:0000313|Proteomes:UP000007978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS3096 {ECO:0000313|EMBL:EKJ69139.1,
RC ECO:0000313|Proteomes:UP000007978};
RX PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT "Comparative pathogenomics reveals horizontally acquired novel virulence
RT genes in fungi infecting cereal hosts.";
RL PLoS Pathog. 8:E1002952-E1002952(2012).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971,
CC ECO:0000256|PIRSR:PIRSR602403-1};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ69139.1}.
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DR EMBL; AFNW01000359; EKJ69139.1; -; Genomic_DNA.
DR RefSeq; XP_009262075.1; XM_009263800.1.
DR AlphaFoldDB; K3V7H0; -.
DR EnsemblFungi; EKJ69139; EKJ69139; FPSE_10683.
DR GeneID; 20369300; -.
DR KEGG; fpu:FPSE_10683; -.
DR eggNOG; KOG0156; Eukaryota.
DR HOGENOM; CLU_022195_0_3_1; -.
DR OrthoDB; 1351063at2759; -.
DR Proteomes; UP000007978; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11041; CYP503A1-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002403; Cyt_P450_E_grp-IV.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR46206; CYTOCHROME P450; 1.
DR PANTHER; PTHR46206:SF3; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00465; EP450IV.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR602403-1};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR602403-1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR602403-1};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000007978};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT BINDING 442
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR602403-1"
SQ SEQUENCE 506 AA; 57886 MW; 61CDE56F57A105AF CRC64;
MSTYIDIVLG NPQYAVFTTI SLIAILITNY SFFAKDDKYP VLNPKKPFEW SNTRVVKQFT
ENSKSLLAHA RSVYGEKPYR VYTDVGKVLV IPPSWVHALR GKKELNFRIP DSLSFIPGFD
GFSFHSNIGT VVTKYVTKSL SKLTGPLSEE ASLSIRDRLT DSTEWHSINP PKEIIRIVSR
VSSRIFMGKE LCRDEGWTKA SSDYTMVAFG SLALVREYPR WLRPYIHWFL PCCKEARRKL
NEARECLQPH LDRRAVIKQQ ALAQGQPYPF DDAIEWFNKE YDAHDPATQQ IAISIVAYHT
TSDLLCETLF NLCRHPEFFK PLRDELVTVL SREGGMTKAA LYNLKLMDSV IKESQRLRPI
LLGVFRRVAL ANVTLPNGDI LRKGDRVIGE TTHMWGPELY DNALEFDPYR FVRMRESGEE
HKAHLVSTSP DHLGFGHGVH ACPGRFLAAN EIKILLCHLL LKYDWKLPEG AEPKSSFVGF
RLDGDKSTNL LVRRRTEELD LDSLSF
//
