ID   K3VQI1_FUSPC            Unreviewed;       747 AA.
AC   K3VQI1;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN   ORFNames=FPSE_02529 {ECO:0000313|EMBL:EKJ77254.1};
OS   Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ77254.1, ECO:0000313|Proteomes:UP000007978};
RN   [1] {ECO:0000313|EMBL:EKJ77254.1, ECO:0000313|Proteomes:UP000007978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CS3096 {ECO:0000313|EMBL:EKJ77254.1,
RC   ECO:0000313|Proteomes:UP000007978};
RX   PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA   Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA   Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT   "Comparative pathogenomics reveals horizontally acquired novel virulence
RT   genes in fungi infecting cereal hosts.";
RL   PLoS Pathog. 8:E1002952-E1002952(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKJ77254.1}.
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DR   EMBL; AFNW01000060; EKJ77254.1; -; Genomic_DNA.
DR   RefSeq; XP_009253923.1; XM_009255648.1.
DR   AlphaFoldDB; K3VQI1; -.
DR   EnsemblFungi; EKJ77254; EKJ77254; FPSE_02529.
DR   GeneID; 20361148; -.
DR   KEGG; fpu:FPSE_02529; -.
DR   eggNOG; KOG0191; Eukaryota.
DR   HOGENOM; CLU_021868_0_0_1; -.
DR   OrthoDB; 52245at2759; -.
DR   Proteomes; UP000007978; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd02961; PDI_a_family; 2.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 3.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR45672; PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED; 1.
DR   PANTHER; PTHR45672:SF3; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5; 1.
DR   Pfam; PF00085; Thioredoxin; 2.
DR   Pfam; PF13848; Thioredoxin_6; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 3.
DR   PROSITE; PS51352; THIOREDOXIN_2; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007978};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..747
FT                   /note="Thioredoxin domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003866980"
FT   TRANSMEM        697..714
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          16..158
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   DOMAIN          278..396
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REGION          160..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..215
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        222..263
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   747 AA;  84632 MW;  10046362AC42A285 CRC64;
     MRFSPLATLA GLSAFVLADE VKNPVSEPSV FNGKTVPPLL ELTPANWEEQ TKKNKFLMVK
     HFSPYCKHCT RFAPTFQTLY EFYYTSKPQV DDPEATFTKY YDFVFGTVNC VAYYDFCMEH
     EIQSYPTSIL YEDGKVFESL RGIKNMTVLT TTIEKALAKT HPGRPELVEL PNPGDKVYPA
     PKTDEKPAES ATEKKEAEAP AKAAAEAEKP LDAAAEKVAS EPAGKTEGKS LDDVTKMPKD
     EDKSDKAEVV EKTAQDENKH SFGADWKVPS TGQMLKKPKA QNPTPKYNLE GISAPLTPAN
     FDTLVTNSKD PWFIKFYAPW CSHCKAMAPT WQQLAKKMQG KLNIGEVNCE ADHKLCTQMG
     VKAFPTIHFI NGAEKAEYKG LRGVGDFVAY AEGALEVAGG VLDVDAESFK ELEKTEEVLF
     VYFYDHATTT EDFKALDALP LNLIGRGKIV KTSDPELFSR FKITTWPRLL VSREGRATYY
     TPITPDEMRD VDSLVSWMKS TWLPLVPEMT AINAKQIMNH KLVVLAILNR DDEDRLQNSI
     SELKNAANEW VDRQVQEFQL ERKKLRDAKQ MRIEEAQSRD DQRGLRNAKA IKIDMDSTRR
     QEVGFAWVDG IFWQRWIAST YNIDVRDGER IIINEEDRHK FWDTTPTGNQ IMVSHTSIMD
     TLDKIVYGPN PISPKYTISS FAKFFFDIKM NFVDHPFLSI GFVIAVGFGL YSWFRNRTRR
     SRGTFFRDDN MGLKDGLLGQ NGNAKSD
//