ID K3XE93_SETIT Unreviewed; 946 AA.
AC K3XE93;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN Name=101770863 {ECO:0000313|EnsemblPlants:KQL07503};
GN ORFNames=SETIT_5G362400v2 {ECO:0000313|EMBL:RCV27902.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV27902.1};
RN [1] {ECO:0000313|EMBL:RCV27902.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL07503,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV27902.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV27902.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV27902.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL07503}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL07503};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; AGNK02003342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003532; RCV27902.1; -; Genomic_DNA.
DR RefSeq; XP_004970391.1; XM_004970334.2.
DR AlphaFoldDB; K3XE93; -.
DR EnsemblPlants; KQL07503; KQL07503; SETIT_000210mg.
DR GeneID; 101770863; -.
DR Gramene; KQL07503; KQL07503; SETIT_000210mg.
DR KEGG; sita:101770863; -.
DR eggNOG; ENOG502QT06; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR InParanoid; K3XE93; -.
DR OMA; FGHNLFT; -.
DR OrthoDB; 394505at2759; -.
DR Proteomes; UP000004995; Chromosome V.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR48054:SF30; LEUCINE-RICH REPEAT PROTEIN KINASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48054; RECEPTOR KINASE-LIKE PROTEIN XA21; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 6.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..946
FT /note="Protein kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010125634"
FT TRANSMEM 581..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 662..934
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 549..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 691
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 946 AA; 100732 MW; 44C4471FB407D5D2 CRC64;
MAAACPPLLL AALLLAAAAA TSALTDDVLA LVVFKTGVSD PSGRLATWTE DDDRPCSWPG
VGCDARTGRV TSLSLPAASL SGRLPPALLR LDALLSLALP RNNLSGPVLP NLLAALPRLR
SLDLSSNRLA APVPAQLFAQ CRYIRAISLA HNQLSGYIPP AVTSCASLVS LNLSSNRLAG
PIPDGLWSLP SLRSLDLSGN ELSGSVPGGF PRSSSLRQVD LSRNLLAGEI PADVGEAALL
KSLDFGHNLF TGGLPESLRR LTGLQFLGAG GNALAGELPA WIGEMRALER LDLSGNRFAG
DISYTIANCK NLVEVDLSRN ALTGELPWWV FGLPLQRVSV AGNQLHGWVK VPEDAAMALR
VLDLSRNAFS GEIPSRITAF AGLQSLNLSS NSLSGQLPAG IGGMRLLEVL DVSANRLDGT
VPPEIGGAVA LRDLRMGRNS LTGGIPAQIG NCSSLVALDL SHNSLTGPIP STMGNLTSLQ
VVNLSQNKLN GTLPVELSNL PSLHIFDVSH NMLTGDLPNS RFFNNIPDSF VMDNSGLCSS
RKNDSCSAVM PKPIVLNPNS SSNPSSQATS SAPSNKHHKK IILSISTLIA IAGGAAIAIG
VITISVLNRR VRARAAASRS APATALSDDY LSQSPENDAS SGKLVMFGKG SPEFSAGGHA
LLNKDCELGR GGFGAVYKTV LRDGQPVAIK KLTVSSLVKS KDDFERQVKM LSKVRHHNIV
ALRGFYWTSS LQLLIYDYLP GGNLHKQLHE CTEDNSLSWM ERFDIILGVA RGLTYLHQHG
IIHYNLKSSN VLLDSNGEPK VGDYGLAKLL PMLDRYVLSS KIQSSLGYMA PEFACKTVKI
TEKCDVYGFG VLVLEVLTGR RPVEYLEDDV VVLCDLVRST LEEGRPEDCI DPRLCGEFPM
DEALPIIKLG LVCTSQVPSN RPDMGEVVSI LELVRSPQDS AEEELV
//
