ID K3XEW8_SETIT Unreviewed; 738 AA.
AC K3XEW8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL03172, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL03172, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL03172,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL03172}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL03172};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; AGNK02002730; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3XEW8; -.
DR EnsemblPlants; KQL03172; KQL03172; SETIT_000435mg.
DR Gramene; KQL03172; KQL03172; SETIT_000435mg.
DR eggNOG; KOG1012; Eukaryota.
DR HOGENOM; CLU_017566_0_0_1; -.
DR InParanoid; K3XEW8; -.
DR OMA; YMGRNSP; -.
DR Proteomes; UP000004995; Chromosome V.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd00030; C2; 1.
DR CDD; cd21669; SMP_SF; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR031468; SMP_LBD.
DR InterPro; IPR039010; Synaptotagmin_SMP.
DR PANTHER; PTHR47042; C2 DOMAIN-CONTAINING PROTEIN-LIKE; 1.
DR PANTHER; PTHR47042:SF1; OS01G0242600 PROTEIN; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF17047; SMP_LBD; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51847; SMP; 1.
PE 4: Predicted;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00023055}.
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..320
FT /note="SMP-LTD"
FT /evidence="ECO:0000259|PROSITE:PS51847"
FT DOMAIN 326..440
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..625
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 82549 MW; 5A286DA100BD3B58 CRC64;
MGSDEAGQLV GGRRKTKPSS KPSQQSPPSH SIHITPRHLP PYFSPSSRTP RRRRTLMDAA
ELPLVYHIGL VLAALWAAGA LGIRHSFLFL LAFLYLYMVN ARCAMRLRKR IQHEEMKSAY
QRRLLSDAES VRWLNHAINK MWPICMEKIV SQLLRPIIPW FLDKFKPWTV SKASVQELYM
GRNPPMFTSM RVLPETSDDD HLVLELGMNF LSAEDMSAIL AMQLHKSVGL GMTANMHLTS
MHVEGKILVG VKFVRSWPFL GRVRLCFVEP PYFQMTVKPL INHGLDVTEF PGISGWLDKL
MDTAFGQTLV EPNMIVINVE KFASTPSENN WFSIEERPPI AYVKLEILEG TDMKPSDING
LADPYVKGRL GPFKFQTEIQ RKTLSPKWFE EFKIPITSWE ASNELVMEVR DKDPMFDDSL
GGCTIDLHEL RGGQRHDKWI SLNNVKKGRI HLAVTVEDIS EDKNVSCSDE PLKKADAELP
VLTSADSTTD AGELPEEKKV LMDEVEHINI DGQEQPGGLY VHRPGAGVPK TWESRKGRAR
APDTQIYQEV DKSKEIPAPK SSGHGGLFNL GSFFRKNSRK ESFKGDPSLP TTPGSQSVTE
LDPKLPKTPH PNLKELGEKR TSIKLVVNEE ASPASKVGDT DNSTEDVAKV IQKNAGEPGR
SLTSTLSRNI SRKREEDRLS DIQEQIEAHG SESVTVSEEH IPVEGEPIEK EGHQTTEHEN
GDGAEEDSVG AEIATQAS
//
