ID K3XV10_SETIT Unreviewed; 1013 AA.
AC K3XV10;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL10941, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL10941, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL10941,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL10941}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL10941};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; AGNK02002545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3XV10; -.
DR EnsemblPlants; KQL10941; KQL10941; SETIT_005767mg.
DR Gramene; KQL10941; KQL10941; SETIT_005767mg.
DR eggNOG; ENOG502QPYS; Eukaryota.
DR HOGENOM; CLU_000288_22_0_1; -.
DR InParanoid; K3XV10; -.
DR OMA; NTGIFCN; -.
DR Proteomes; UP000004995; Chromosome IV.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF222; OS08G0248100 PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 6.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1013
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010126074"
FT TRANSMEM 648..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 708..1003
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 739
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1013 AA; 110927 MW; 51E9AA5856800CCE CRC64;
MVPMLSLLAH ILLLASSSVS IYHVNDDLSV LLSFKYYIKN DPGQALSSWD ATDNGTNNLS
TDFCRWNGIA CNDRRHPGRV TAIRLRGSDL GGTISPHIGN LTQLQHIDLS QNNLLGEIPV
SLGSCTELRT MNLSVNQLSG SLFPDPLGHL SKLKVFNVRH NNLTGVIPIT LSNLTALTNL
SVESNNLQGQ IPSWLCNLTS LAAIDLAHNG LDGHIPSELG KLTKVATLMI QGNQLEGPVP
ASIFNISSIQ HLDLRFNQLS GSLPLDIGFQ LPNILFFATS GNQFEGLIPA SFSNASALES
FLIRRNQYHG LIPRDIGIQC NLKLFSVGYN QFQTSQPREW DFLTSLNNCS KLQLLDLEQN
NFVGIMPVTI ANLSKELTWL TIARNQIAGT IAELGMFQKL IMLTLGDNLF TGTLPVDIGR
LRSLQILDLS HNRFEGQIPQ SLGNITGLSK LSISNNYLNG TIPTSLGKLR ALASMDISCN
FLSGRIPQEI LSIPALTILL KLSNNALSGS IPTQIGHLNN LIAIDLSMNK LTGEIPDDIG
SCVQLQLLHL QGNILQGKLP KGLEKLGVLE NLDLSRNNLI GPIPEFLERI KTLNHLNLSF
NNLSGPVPDT GIFCNATILS LTGNSMLCGG PPFLQFPSCA SVHSQHRMHL LIVFCIPGTL
IFLLFSITTY CCIKRRVKPN IVYQENLFLS EAHERISYNQ LRSATQSFSP ANLIGSGSFG
NVYIGTFIID ENLATVAIKV INLNLRGASR SFLTECNALR RIRHRNLVKV ITVCSGLDHN
GDEFKALVLE FICNGSLDEW LHPNTMENSM TAKRLSLMRR LCIALDVAVA LEYLHHNIEP
PIVHSDIKPS NILLDDDLVA HVTDFGLAKI MYAEVWNKNH GGNESSSLAV KGTIGYVPPY
GSGYGVSTDG DIYSYGVLLL EMLTGKRPTD SFDHGTSLVS YVKMAYPNKL LEILDVSATY
SGNTQDVIDL VIHPMFGIAL ACCQDSPRQR IKMDYVVEEL KAIKKACAAL MGS
//
