ID K3XVA3_SETIT Unreviewed; 828 AA.
AC K3XVA3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=HMA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=101757297 {ECO:0000313|EnsemblPlants:KQL11874};
GN ORFNames=SETIT_4G253000v2 {ECO:0000313|EMBL:RCV22859.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL11874, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV22859.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL11874,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV22859.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV22859.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV22859.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL11874}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL11874};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|RuleBase:RU362081}.
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DR EMBL; AGNK02002654; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003531; RCV22859.1; -; Genomic_DNA.
DR RefSeq; XP_004966187.1; XM_004966130.3.
DR RefSeq; XP_012701050.1; XM_012845596.2.
DR AlphaFoldDB; K3XVA3; -.
DR STRING; 4555.K3XVA3; -.
DR EnsemblPlants; KQL11874; KQL11874; SETIT_005860mg.
DR GeneID; 101757297; -.
DR Gramene; KQL11874; KQL11874; SETIT_005860mg.
DR KEGG; sita:101757297; -.
DR eggNOG; KOG0207; Eukaryota.
DR HOGENOM; CLU_001771_6_3_1; -.
DR InParanoid; K3XVA3; -.
DR OMA; SPTWSWV; -.
DR OrthoDB; 1711at2759; -.
DR Proteomes; UP000004995; Chromosome IV.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43079:SF1; CADMIUM_ZINC-TRANSPORTING ATPASE HMA1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43079; PROBABLE CADMIUM/ZINC-TRANSPORTING ATPASE HMA1; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 161..182
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 188..206
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 408..432
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..96
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 828 AA; 88235 MW; 94E7B1149F5789CD CRC64;
MQFLTASASV SSPAPPSAHL LRLSRPPPFP HLRRRCSPPK PLALTRRPPL LLASRQSPLF
APRAHGGHGH SHHHHGHDHH HHHHGHDHHH HGHGHHGVDT HGGGGGAAVM RVARAIGWAD
VASALRENLQ LCCISLGLLL IAAVCPHVAL LSSVGRLQAT LIAVAFPLVG VSAALDALVN
IADGRINIHV LMALAAFASI FMGNALEGGL LLAMFNLAHI AEEYFTSKSM FDVRELKENH
PEFALLLETS GEESVQFSNL SYTRVPVHDL EVGSHILVRA GEAVPVDGEV YQGSSTVTIE
HLTGETKPLE RTVGDAIPGG ARNLEGMMIV KVTKSWEDST LNRIVQLTEE GQLNKPKLQR
WLDEFGEYYS RVVVALSLAV ALLGPLLFKW PFFGNSVCRG SIYRGLGLMV AASPCALAVA
PLAYATAISS LASKGILLKG GHVLDALSAC QSIAFDKTGT LTTGKLTCKA IEPIHGHLGV
TNGHSDPSCC TPNCESEALA VAAAMEKGTT HPIGRAVLDH SVGKELPAVA VESFECLPGR
GVAATLSGVK ARNSENELSE ASIGSVDYIS SLYRSNGESE QIKQAVKGSA YGPEFVQAAL
SVDKKVTLFH FEDEPRSGVC EVIHTLREKA KLRIMMLTGD HESSAQRVAK AVCIDEVHFS
LKPEDKLDKV KAVSRERGGG LIMVGDGIND APALAAATVG MVLAQRASAT AVAVADVLLL
QDNICGVPFC IAKARQTTSL VKQSVALALT CIVFAALPSV LGFLPLWLTV LLHEGGTLLV
CLNSIRALNT PTWSLVDDIR QLFDGLRNYF SSKFNNSSSN YVANTVPL
//
