ID K3Y6Q4_SETIT Unreviewed; 506 AA.
AC K3Y6Q4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN Name=101777940 {ECO:0000313|EnsemblPlants:KQK99919};
GN ORFNames=SETIT_7G323900v2 {ECO:0000313|EMBL:RCV36501.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV36501.1};
RN [1] {ECO:0000313|EMBL:RCV36501.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK99919,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV36501.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV36501.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV36501.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK99919}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK99919};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|ARBA:ARBA00008723,
CC ECO:0000256|RuleBase:RU361203}.
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DR EMBL; AGNK02004585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003534; RCV36501.1; -; Genomic_DNA.
DR EMBL; CM003534; RCV36502.1; -; Genomic_DNA.
DR RefSeq; XP_004977563.1; XM_004977506.1.
DR AlphaFoldDB; K3Y6Q4; -.
DR EnsemblPlants; KQK99919; KQK99919; SETIT_009880mg.
DR GeneID; 101777940; -.
DR Gramene; KQK99919; KQK99919; SETIT_009880mg.
DR HOGENOM; CLU_013387_0_0_1; -.
DR OrthoDB; 5485592at2759; -.
DR Proteomes; UP000004995; Chromosome VII.
DR ExpressionAtlas; K3Y6Q4; baseline.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR039331; PPA-like.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR PANTHER; PTHR22953:SF108; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 112..199
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 208..400
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 415..480
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 506 AA; 56277 MW; 3717E6B7D496B540 CRC64;
MCKIARVAAA LIRVLYLVAV AAPVKSLLAV AKVAFSLVNA PCLRYMNQAA LGRSCTGTFC
GDLLVGAMAH SWRMLVQGLT SLMFFCAHAD EYVRPPPSPL VLMAHDKPAS HPQQVHISVV
GPNHMRISWV TDDRNAPSVV EYGTSPGKYT ASATGNHTTY HYFFYKSGAI HHVTIGPLEP
VTTYYYRCGR AGDEFSFRTP PATLPIEFVV IGDLGQTGWT ASTLSHIGGG DYDMLLLPGD
LSYADTQQPL WDSFGRLVQP LASARPWMVT EGNHEMETLP VVEFAPFAAY NARWRMPHEE
SGSRSNLYYS FDAAGGAAHV VMLGSYAAFG EGSEQHRWLE ADLARVDRRR TPWLLVLLHA
PWYNTNQAHQ GEGERMRLAM ERMLYEARVD VVFAGHVHAY ERFTRIYDNE ADSRGPMYIT
IGDGGNREGL ALRFIEDHKS AHLSVFREAS FGHGRLRIVN ETSAVWTWHR NDDEYATVRD
EVWLESLAAA KPSLATTTAG RHTDEL
//
