ID K3Y752_SETIT Unreviewed; 462 AA.
AC K3Y752;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=3-ketoacyl-CoA synthase {ECO:0000256|PIRNR:PIRNR036417};
DE EC=2.3.1.- {ECO:0000256|PIRNR:PIRNR036417};
GN Name=101766849 {ECO:0000313|EnsemblPlants:KQK97187};
GN ORFNames=SETIT_7G091500v2 {ECO:0000313|EMBL:RCV33551.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQK97187, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV33551.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK97187,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV33551.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV33551.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV33551.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK97187}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK97187};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|PIRNR:PIRNR036417}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|PIRNR:PIRNR036417}.
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DR EMBL; AGNK02004333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003534; RCV33551.1; -; Genomic_DNA.
DR RefSeq; XP_004975571.1; XM_004975514.2.
DR AlphaFoldDB; K3Y752; -.
DR STRING; 4555.K3Y752; -.
DR EnsemblPlants; KQK97187; KQK97187; SETIT_010043mg.
DR GeneID; 101766849; -.
DR Gramene; KQK97187; KQK97187; SETIT_010043mg.
DR KEGG; sita:101766849; -.
DR eggNOG; ENOG502QPKZ; Eukaryota.
DR HOGENOM; CLU_013238_2_1_1; -.
DR InParanoid; K3Y752; -.
DR OMA; HKIINKF; -.
DR OrthoDB; 341321at2759; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000004995; Chromosome VII.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR012392; 3-ktacl-CoA_syn.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013601; FAE1_typ3_polyketide_synth.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR31561; 3-KETOACYL-COA SYNTHASE; 1.
DR PANTHER; PTHR31561:SF111; 3-KETOACYL-COA SYNTHASE; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR Pfam; PF08392; FAE1_CUT1_RppA; 1.
DR PIRSF; PIRSF036417; 3-ktacl-CoA_syn; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|PIRNR:PIRNR036417};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transferase {ECO:0000256|PIRNR:PIRNR036417};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..329
FT /note="FAE"
FT /evidence="ECO:0000259|Pfam:PF08392"
FT DOMAIN 351..431
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 462 AA; 51028 MW; 516945B615182229 CRC64;
MAVVAALQRA WVLVSHGELV GLLTPLHVVM AFTLGAGVVM LWRVCRSRDV YLVDYGCFLG
EPRHRVPFAM ALEHGRLMTW FVDDESTKFM VRLYERSAIG EETSVPDSYR YMPPERGVEA
SREEAELVIF SAVDKAFARS TLNPGDIDTL IVTCSFTTLT PEFADVIVNR YKLRAEVRSV
NLSGMGCSGA LICVGLAKNL LQVAPPGSHV LIVATEILSS MFYTGTKREM LVPNVLFRMG
AAAIIMSNSP ERARFRLGPI VRTLTAAKDG DYRCAFQEED DEGITGINLS KDLPVVAANA
LKSHIIAFGP AVLPVSVLLR VAFSFLRHRF SSGEARAEER CYRPAFHNVF QHFCIHPGGR
RVLYEVQRGL GLSDGDMEAS HMTLHRFGNM ASSSLLYELA YIEAKGRMSK GDRVCMISFS
PGIDCSSVVW ECIKAAAEPG DGPWAGCIHR YPVQLPKILK RT
//
