ID K3YG21_SETIT Unreviewed; 993 AA.
AC K3YG21;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE RecName: Full=USP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=101781257 {ECO:0000313|EnsemblPlants:KQL02212};
GN ORFNames=SETIT_6G185200v2 {ECO:0000313|EMBL:RCV31529.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL02212, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV31529.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL02212,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV31529.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV31529.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV31529.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL02212}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL02212};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C19 family.
CC {ECO:0000256|ARBA:ARBA00009085}.
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DR EMBL; AGNK02003939; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003533; RCV31529.1; -; Genomic_DNA.
DR RefSeq; XP_004973704.1; XM_004973647.3.
DR AlphaFoldDB; K3YG21; -.
DR EnsemblPlants; KQL02212; KQL02212; SETIT_013189mg.
DR GeneID; 101781257; -.
DR Gramene; KQL02212; KQL02212; SETIT_013189mg.
DR KEGG; sita:101781257; -.
DR eggNOG; KOG1865; Eukaryota.
DR HOGENOM; CLU_007397_0_0_1; -.
DR InParanoid; K3YG21; -.
DR OMA; APVENEY; -.
DR OrthoDB; 227085at2759; -.
DR Proteomes; UP000004995; Chromosome VI.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF874; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..152
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 460..766
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 148..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..877
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..982
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 108751 MW; BAC7CCA918886896 CRC64;
MEEEVESSSA AAAVVLALVA LVVVPALALL VRSRWRRAAA RRDEVRRLAR LAAEESELAE
RESVLAYYSE LFPAVVHAAE VPEAPVWGPP PAAVAPAQED VEAQPQPPAG AKGVCAVCFR
PTTFRCKQCK AVKYCSFKCQ IAHWRQGHKD ECHPPSVNTR PDDEGRVEQE RAAEENVSVG
VKPIAETNKP VTIGDETSDE NHSLKSSIGE GKHMPLEDLC TSTEVPGGHK SNGTVEIPQN
VPVSVDGSKM ASNTEHATFV EDGSSSKDLN EVLPCNSQAT DPKTSGRSSS FNGESFNHSK
EHHKAQDASI IEDCSQTSHN RELEDSGNPR AAASVVLETK SSRNPIRVEL ERSKTKSVGN
DNVQSTKPVL TASTAEKATS IRGGCSVIPI PSKVSDNCSD RSSKPSERSG STANNLATSL
KKIVRQQTAS KVVRHYPSEL TLFPYELFVK LYDKVELHPF GLHNLGNSCY ANAVLQCLMF
TRPLTTYLLG GLHSKNCSKR EWCFMCEFEK LIVEGKRRKT ALSPTGILSH LHDIGSSFGP
GKQEDAHEFL RYAIDAMQSV CMKEARKGGA LRSAEETTLV QLIFGGYLRS KIKCSRCHIS
SEQCERMLDL TVEIDGDISS LDEALVRFTS TEVLDGENRY HCSRCKSYER AKKKLTIEEA
PNVLTIALKR YQSGKFGKIN KAIRFPETLN MVRYMNPETD DRSPVYSLYA VVVHHDVMNA
AFSGHYVCYV KDTQGKWFKA DDSQVKPVSL DNVMSKCAYM LLYARCSPRA PSSVRKVMVQ
DPARPKKAKQ KVVPGGTPFG GSFSRHQGGH LHADYMADDL AHTSDEYGDA PYPPAESPSP
SESSSLFSNS DAGSHSTVST DSSDSTRNST STEEYEYLFG ASDQMYPGAP VENEYPTYSR
SRSSLNTSSS GGVADDAERF AEHKPQGGGA GGGWVVGDES PSLLYTDRSK HQSSSKLTDQ
YRQLDRSGHD PGETRGGVLL RRSARDRTAQ TFY
//
