ID K3YQG7_SETIT Unreviewed; 696 AA.
AC K3YQG7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=SPX domain-containing protein {ECO:0000259|PROSITE:PS51382};
GN Name=101754776 {ECO:0000313|EnsemblPlants:KQL30929};
GN ORFNames=SETIT_1G271500v2 {ECO:0000313|EMBL:RCV07758.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL30929, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV07758.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL30929,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV07758.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV07758.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV07758.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL30929}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL30929};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNK02000493; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003528; RCV07758.1; -; Genomic_DNA.
DR EMBL; CM003528; RCV07759.1; -; Genomic_DNA.
DR RefSeq; XP_004953440.1; XM_004953383.2.
DR RefSeq; XP_004953441.1; XM_004953384.2.
DR RefSeq; XP_012698738.1; XM_012843284.2.
DR RefSeq; XP_012698739.1; XM_012843285.2.
DR AlphaFoldDB; K3YQG7; -.
DR STRING; 4555.K3YQG7; -.
DR EnsemblPlants; KQL30928; KQL30928; SETIT_016511mg.
DR EnsemblPlants; KQL30929; KQL30929; SETIT_016511mg.
DR GeneID; 101754776; -.
DR Gramene; KQL30928; KQL30928; SETIT_016511mg.
DR Gramene; KQL30929; KQL30929; SETIT_016511mg.
DR KEGG; sita:101754776; -.
DR eggNOG; KOG1161; Eukaryota.
DR eggNOG; KOG2325; Eukaryota.
DR HOGENOM; CLU_025236_1_0_1; -.
DR InParanoid; K3YQG7; -.
DR OMA; RANHPCS; -.
DR OrthoDB; 54041at2759; -.
DR Proteomes; UP000004995; Chromosome I.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd14479; SPX-MFS_plant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR045264; SPXM_SPX_plant.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF23; SPX DOMAIN-CONTAINING MEMBRANE PROTEIN OS02G45520; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF03105; SPX; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..145
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REGION 439..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 77739 MW; 08B85E87C6082CE5 CRC64;
MVNFGKRLVA DQLEEWREYY INYKMMKKKV KQYVQQTQTG GKNREQVLKE FSRMLDDQIE
KIVLFLLQQQ GHLASRIENL GEQRAALMEQ SDVSQICQLR EAYREVGYDL VKLLRFLDMN
ATGIRKILKK FDKRFGYKFT DYYVSTRANH PYSQLQQIFK QVGVVAVVGA LSRNLAYLQD
HRGSFSSIYD HPSITFKDPV IEQINHSVQK LTHSTNFLQF LGQHALIVPD DMHSGSDLVD
DQSYHFLSLL LNLVNTFLYM VNTYIIVPTA DDYSVSLGAA ATVCGVIIGS MAVAQIFSSV
YFSAWSNRSY FRPLVFSSIM LFLGNLLYAL AYDLNSLTVL IVGRLLCGLG SARAVNRRYI
SDCVPLKTRL QASAGFVSAS ALGMACGPAL AGLLQTKFRI YGLTFNQNTL PGWVMCVAWL
VYLCWLWISF KEPGHIATDN SVNSQSSDSD HQVSGNLEDG LGQPLLVDVK ERHDEDGEDN
DDNEEDPEES HKPATSLAAA YRLLTPSVKV QLLIYFMLKF AMEILLSESS VVTTFYFNWT
TSTVAIFLAV LGLTVLPVNV IVGSYVTNLF QDRQILVASE IMVLIGIVMS FCFTPQYSVP
QYVTSALITF VFSEVLEGVN LSLLSRVMSS RLSRGTYNGG LLSTEAGTLA RVAADMTITA
AGYLGQSRLL NATLLPSLLI CVASIVATFC TYNSLY
//
