ID K3YYL4_SETIT Unreviewed; 928 AA.
AC K3YYL4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL30427, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL30427, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL30427,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL30427}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL30427};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNK02000428; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3YYL4; -.
DR EnsemblPlants; KQL30427; KQL30427; SETIT_019368mg.
DR Gramene; KQL30427; KQL30427; SETIT_019368mg.
DR eggNOG; ENOG502SJK0; Eukaryota.
DR HOGENOM; CLU_000288_43_0_1; -.
DR InParanoid; K3YYL4; -.
DR OMA; PKLFWAN; -.
DR Proteomes; UP000004995; Chromosome I.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR045274; WAK-like.
DR InterPro; IPR025287; WAK_GUB.
DR PANTHER; PTHR27005:SF559; EGF-LIKE CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR27005; WALL-ASSOCIATED RECEPTOR KINASE-LIKE 21; 1.
DR Pfam; PF13947; GUB_WAK_bind; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 514..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 591..865
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 619
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 928 AA; 101924 MW; 31894A94817D670C CRC64;
GAPRAPGVAG AGGGILSVPS ATSLAHCPTR CGDAEFLYPF GTEPGCFRQG FELTCDTTTQ
PPKLFWANTL YQMVGTDRTD HWFAYASIGF SITMTPGTST YTRSLESPAR GFIIDSDTHM
FAVGCDVEVL LFDTGTNLTI GSCTSSCPGD RATMSNESVA VAGNCNGLGC CSIALPDYLQ
GFRFILSRRD GVIRARSDAQ ASINVKVFLT QDYEFETSDL YSSWINRSVH TSLEIFATDQ
PSCEIASANK ETYACSPGSS CQTGKWGGYF CYCNPGVNGN NPYILDGCIE GYNPHPKGNC
KRSCGNMSIP FPFGLEEGCF AHQKFRLSCV SDKFVVLNRE DGTKYKVTTL QVDDGYLGVT
SMLNDSSSSD DEVVVVHTTD GDFDYRVPRE AMRNLIEFSQ EFDIRMRWAV SNLTCGTASQ
RSTTYACISA HSQCVNVTHG TLYLGYRCKC LPGFYGNPYV QDGCKDIDEC LEPNNCNGLC
HNTPGGYYCS SCPHGKVFVP TKRKCVTSAK QHNLLFGIAI GIGCGLSSII LALCATIIAR
KWKQGRRKRM RRAYFKKNQG LLLEQLISDE STTNKTKIFS LEELEKATNN FDAARVLGRG
GHGTVYKGIL SDQNVVAIKI SKIAEQIEID QFINEVAILS QIIHRNVVKL FGCCLETEVP
LLVYEFISNG TLYSLLHSNA SAKCLLSWDD RIRIAVESSG ALAYLHSAAA IPIFHRDVKS
SNILLDASFS TKVSDFGASR SVSLDETHVV TIVQGTFGYL DPEYYHTGQL TGKSDVYSFG
VILVELLTRK KPIFINDSGM KQSLSHYFSE KLQEGAIMEI IDSQIVEEAD QGEIGDLISL
AQACLRTKGG ERPTMKEVEM KLQFLRTRRP RKVHDLPGTN GEIGHLFCPQ DTNSHTRLDL
VNAARLPSED TRGYSLEKEF ASSISLPR
//
