ID K3Z5P7_SETIT Unreviewed; 494 AA.
AC K3Z5P7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=101766884 {ECO:0000313|EnsemblPlants:KQL15448};
GN Synonyms=MLO {ECO:0000256|RuleBase:RU280816};
GN ORFNames=SETIT_3G239300v2 {ECO:0000313|EMBL:RCV17686.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV17686.1};
RN [1] {ECO:0000313|EMBL:RCV17686.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL15448,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV17686.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV17686.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV17686.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL15448}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL15448};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
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DR EMBL; AGNK02001712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003530; RCV17686.1; -; Genomic_DNA.
DR RefSeq; XP_004962062.1; XM_004962005.2.
DR AlphaFoldDB; K3Z5P7; -.
DR STRING; 4555.K3Z5P7; -.
DR EnsemblPlants; KQL15448; KQL15448; SETIT_021865mg.
DR GeneID; 101766884; -.
DR Gramene; KQL15448; KQL15448; SETIT_021865mg.
DR KEGG; sita:101766884; -.
DR eggNOG; KOG0017; Eukaryota.
DR InParanoid; K3Z5P7; -.
DR OMA; KIHQWKQ; -.
DR OrthoDB; 368831at2759; -.
DR Proteomes; UP000004995; Chromosome III.
DR ExpressionAtlas; K3Z5P7; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942:SF129; MLO-LIKE PROTEIN; 1.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR Pfam; PF03094; Mlo; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 494 AA; 55692 MW; 577C7EAB05B4A4AF CRC64;
MAAEGEAAAL EYTPTWIVAA VCSIIVLLSL VAERFLHYIG KKLKKKNQKP LYEALLKVKE
ELMLLGFISL LLTVFQGMIQ RTCIPAGWTD HMLPCQRLDV KAGEINATKE HFVAAGIIGK
IRRRLLSEGG AGADICLKKR KVPLLSVEAI HQLHIFIFVL AITHVIFSVT TMLLGGAQIH
QWKQWENGIQ KDDPGNGPKK VTDVHRHEFI KKRFKGIGKE SIILSWLHSF GKQFYRSVSK
SDYTTMRLGF IMTHCPGNPK FDFHRYMVRV LEADFKKVVG ISWYLWVFVV IFLLLNVNGW
HTYFWIAFLP LFLLLAIGTK LEHVIAQLAH DVAEKHTAIE GEVVVKPSDD HFWFGKPRVI
LFLIHFILFQ NAFEIAFFFW ILSTYGFDSC IMGQVRFIVP RLVIGVLIQL LCSYSTLPLY
AIVTQMGSCY KKEIFNEHVQ QGVLGWAQKV KMRKGLKGAA NKAESTSNAD SAGPSATIEM
AKAGADVEAV GNTE
//
