ID K3ZCR2_SETIT Unreviewed; 1435 AA.
AC K3ZCR2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=SETIT_3G360400v2 {ECO:0000313|EMBL:RCV19141.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV19141.1};
RN [1] {ECO:0000313|EMBL:RCV19141.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL16878,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV19141.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV19141.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV19141.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL16878}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL16878};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; AGNK02002076; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003530; RCV19141.1; -; Genomic_DNA.
DR STRING; 4555.K3ZCR2; -.
DR EnsemblPlants; KQL16878; KQL16878; SETIT_024340mg.
DR Gramene; KQL16878; KQL16878; SETIT_024340mg.
DR eggNOG; KOG0928; Eukaryota.
DR HOGENOM; CLU_001204_1_0_1; -.
DR InParanoid; K3ZCR2; -.
DR OMA; IMIHNIA; -.
DR Proteomes; UP000004995; Chromosome III.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF322; ARF GUANINE-NUCLEOTIDE EXCHANGE FACTOR GNL2; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 516..706
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1435 AA; 156316 MW; A207BEC1149BCC23 CRC64;
MARTAADDDD DGPPPAYAAQ RGPRRDPRLK DLGISCMLNT EVAALLAVIR RRPDPYSYLP
PAVAAAEEAT FAGLISSLKT LRGLLFQPRH GAWRCSDPST YLTPFLDVVQ SDEAPPAATG
VALSSVLKIL RIDVFDECSP GARDAVHAIL AALTSCRMDR ISDASAEEAV LLRVLQVLAA
LLRARAAPLL SDSSVCTAVN TCFQIVQHAA GSRGSELLQR TARHCMHEIL QSVFARLPDI
HDDSAGDADG DVAAGAGASS GAGFGARCMV DVFNFLCSLL QNASDMVITA DGQGAFTSEE
DVMLFSLVLV NSAVELGGEA IGKHAKLLRL IQDDLFYHLI SYATEYSPLV LSMICSTALN
LYHFLRRHLK LQLEAFFMFV LLKVCGGANG PQLQEVAVEG LISFIRQPTF VIEMYVNYDC
DPLLRNVFEE VGKLLCKAAF PSSPGPMTAV QLQAFEGLVN MITTIADNVE VDKAPDTDAY
AVEVSEFRLF WTERWDPSTG AGAAAGNGER ETWVDFVRKR KLRKKKAAIA ANHYNRDQKK
GVEYLKLCHL IPTPPEPRSM AYFLRYSPGL DKNKIGEFLG DPDDFNLKVL KEFTETFDFT
GAILDTALRT YLETFRLPGE SQKIQRILEA FSERFFEQQT TGVFATKDAA FILCYSLIML
NTDLHNPQVK KKMSEEDFIR NNRAINDKKD LPREYLSELF HSISSNAITV FSSSAAAAAE
MTASRWADLV RRSRAMEPFT PCDFRHKLSR EVFVAVSGPA VAALAAVFDS ADDEETLSQC
VEGLVSVARV ARYGLGDVLD ELLCCLCKFT TLLNPYATTE ETLFTFSNEL KPRMATLALF
TIANRFGESV RGAWKNVVDC LLKLKRLKLL PPSVIDPGGG GSAVAERPAG HRHRASVSDA
GGGVIFPPTH KGAGTSRHVS GMIGRFSQFL SLDGGGGSES LLTVGSEFEN NLKIVQQCQA
GRIFTESAKL PDEALQNLGR ALVFAAGGKG QKFSTPVEED ETVGFCWDLL ALLASANLHR
LATFLPPLLD CFAAVSQLPL FSPCPFAEKA IVALFRVAVR LLSAPPQPPK PGAADGRVAE
ELVFKSINMM WKLDKEILDT CCEGISESVV RLLTEHAGGV QTPLGWKTLL HLLTVTGRHP
ETFDQSVAAM IKVMSDDGAH VTRFNYAAVI EAAFGFAALK ISPLDVSTKI LELMAESVNW
LVQWHKSGYS DPGNSAGFSG GGGSSSSSAT SVDAADASRM GNLATNMFIK LAEALRKTSL
VRREEIRCQA VFELGRAFNL AAAGDLDFGP GGCLACFNLV IFAMVDDLTE KTLEYSRREG
AERETRSMEG TLAAAAELLA DVFVLLLPML AQAPGFRTFW LGVLRRMDTC IKCDLAAGGG
AGLMQELVPR MLKRMIMEMK AKEVLVPREG DELWEITYIQ IQWIAPAAKE ELFPE
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