ID K3ZU92_SETIT Unreviewed; 380 AA.
AC K3ZU92;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:RCV10689.1, ECO:0000313|EnsemblPlants:KQL23551};
GN Name=101774246 {ECO:0000313|EnsemblPlants:KQL23551};
GN ORFNames=SETIT_2G129000v2 {ECO:0000313|EMBL:RCV10689.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV10689.1};
RN [1] {ECO:0000313|EMBL:RCV10689.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL23551,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV10689.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV10689.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV10689.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL23551}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL23551};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; AGNK02000884; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003529; RCV10689.1; -; Genomic_DNA.
DR RefSeq; XP_004956157.1; XM_004956100.2.
DR AlphaFoldDB; K3ZU92; -.
DR STRING; 4555.K3ZU92; -.
DR EnsemblPlants; KQL23551; KQL23551; SETIT_030173mg.
DR GeneID; 101774246; -.
DR Gramene; KQL23551; KQL23551; SETIT_030173mg.
DR KEGG; sita:101774246; -.
DR eggNOG; KOG1543; Eukaryota.
DR HOGENOM; CLU_012184_1_0_1; -.
DR InParanoid; K3ZU92; -.
DR OMA; ACKNEVI; -.
DR OrthoDB; 5490122at2759; -.
DR Proteomes; UP000004995; Chromosome II.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF953; CYSTEINE PROTEINASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..380
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009998035"
FT DOMAIN 49..109
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 162..379
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 380 AA; 40217 MW; 26669506A6E24C76 CRC64;
MASTSTNRGS PPRVLLLLLL AAVFLHGCSS ATAAHGRAGG GSTMMVERFQ RWKAEYNRSY
ATAAEERRRF RVFARNLAYI EATNAEAEAA GLTYELGETA FTDLTNEEFT AMYTAAAPLP
PADDEDVAAV ITTRAGPVDA GGVRGAAAGQ QLTAYVNLSA GAPASVDWRA SGAVTPVKNQ
GRCGSCWAFS TVATVEGIYQ IRTGKLVSLS EQELVDCDTL DHGCDGGISY RALRWIADNG
GITTEADYPY TAATGVCDTA KLSHNAVSIA GLRRVATRSE ASLANAVAAQ PVAVSIEAGG
VNFQHYRKGV YNGPCGTKLN HGVTVVGYGQ EPGGGERYWI VKNSWGERWG DGGYIRMRKD
VDGKPEGLCG IAIRPSYPLM
//
