ID K3ZZ53_SETIT Unreviewed; 409 AA.
AC K3ZZ53;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN Name=101786390 {ECO:0000313|EnsemblPlants:KQL23333};
GN ORFNames=SETIT_2G112300v2 {ECO:0000313|EMBL:RCV10437.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL23333, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV10437.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL23333,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV10437.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV10437.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV10437.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL23333}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL23333};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; AGNK02000826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003529; RCV10437.1; -; Genomic_DNA.
DR RefSeq; XP_004956033.1; XM_004955976.1.
DR AlphaFoldDB; K3ZZ53; -.
DR STRING; 4555.K3ZZ53; -.
DR EnsemblPlants; KQL23333; KQL23333; SETIT_031885mg.
DR GeneID; 101786390; -.
DR Gramene; KQL23333; KQL23333; SETIT_031885mg.
DR KEGG; sita:101786390; -.
DR eggNOG; ENOG502QSSY; Eukaryota.
DR HOGENOM; CLU_034992_2_0_1; -.
DR InParanoid; K3ZZ53; -.
DR OMA; ACVRSWG; -.
DR OrthoDB; 883077at2759; -.
DR Proteomes; UP000004995; Chromosome II.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProt.
DR GO; GO:0030639; P:polyketide biosynthetic process; IBA:GO_Central.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF10; TYPE III POLYKETIDE SYNTHASE B; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 16..234
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 243..403
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 170
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 409 AA; 43740 MW; EEF344F25243F15D CRC64;
MVSNDLDTAA AKQASSMAPN PGKATILALG HAFPQQLVMQ DYVVDGFMKN TNCDDPELKE
KLTRLCKTTT VKTRYVVMSD EILKSYPELA QEGLPTMKQR LDISNKAVTQ MATEASLACV
RSWGGALSSI THLVYVSSSE ARFPGGDLHL ARAMGLSPDV RRVMLAFTGC SGGVAGLRVA
KGLAESCPGA RVLLATSETT VVGFRPPSAD RPYDLVGVAL FGDGAGAAVV GADPAPHERP
LFELHSALQC FLPGTDKTIE GRLTEEGIKF QLGRELPHII EAHVEEFCRK LMAEREGGGG
EEEMGYDDMF WAVHPGGPAI LTKMEGRLGL GGDKLRASRC ALRDFGNASS NTIVYVLENM
VEETRRRKAA AAAGDSDGDD CEWGLILAFG PGITFEGILA RNLQAPPRA
//
