ID K4A1Q1_SETIT Unreviewed; 329 AA.
AC K4A1Q1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN Name=101778860 {ECO:0000313|EnsemblPlants:KQL25110};
GN ORFNames=SETIT_2G257600v2 {ECO:0000313|EMBL:RCV12297.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV12297.1};
RN [1] {ECO:0000313|EMBL:RCV12297.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL25110,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV12297.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV12297.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV12297.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL25110}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL25110};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; AGNK02001178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003529; RCV12297.1; -; Genomic_DNA.
DR RefSeq; XP_004957228.1; XM_004957171.1.
DR AlphaFoldDB; K4A1Q1; -.
DR STRING; 4555.K4A1Q1; -.
DR EnsemblPlants; KQL25110; KQL25110; SETIT_032795mg.
DR GeneID; 101778860; -.
DR Gramene; KQL25110; KQL25110; SETIT_032795mg.
DR KEGG; sita:101778860; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_9_0_1; -.
DR InParanoid; K4A1Q1; -.
DR OMA; CEKMQLW; -.
DR OrthoDB; 447101at2759; -.
DR Proteomes; UP000004995; Chromosome II.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR CDD; cd08958; FR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR PANTHER; PTHR10366:SF821; TETRAKETIDE ALPHA-PYRONE REDUCTASE 1; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 9..249
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 329 AA; 36321 MW; B4229EEEBC0E9EE2 CRC64;
MVTSNKGKVC VTGASGFIAS WLIKQLLESG YHVVGTVRDP GNRQKVAHLW KLPGAKERLQ
IVRADLLEEE SFDEAVMSCD GVFHTASPVL AKSDSSSKEA TLVPAVNGTL NVLRSCKKNP
FLKRVVLTSS SSAVRIRDDA QPNISLDETI WSSVPLCEKM QLWYGLAKVF AEKAAWEFAK
ENGIDLVTVL PSFVIGPSLS HELCVTASDV LGLLQGDTAR FSCYGRMGYV HIDDVASSHI
LVYETPEATG RYLCSSVVLD NDELVSFLAK RYPIFPIPRR LDKPYGKQTY QLNTSKLQGL
GFKFRGLQEM FDDCVQSLKD QGHLLECPL
//
