ID K4A8C8_SETIT Unreviewed; 529 AA.
AC K4A8C8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Tyrosine decarboxylase {ECO:0008006|Google:ProtNLM};
GN Name=101783343 {ECO:0000313|EnsemblPlants:KQK86947};
GN ORFNames=SETIT_9G078700v2 {ECO:0000313|EMBL:RCV40732.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV40732.1};
RN [1] {ECO:0000313|EMBL:RCV40732.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK86947,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV40732.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV40732.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV40732.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK86947}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK86947};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC {ECO:0000256|ARBA:ARBA00009533, ECO:0000256|RuleBase:RU000382}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNK02005356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003536; RCV40732.1; -; Genomic_DNA.
DR RefSeq; XP_004981646.1; XM_004981589.2.
DR AlphaFoldDB; K4A8C8; -.
DR STRING; 4555.K4A8C8; -.
DR EnsemblPlants; KQK86947; KQK86947; SETIT_035134mg.
DR GeneID; 101783343; -.
DR Gramene; KQK86947; KQK86947; SETIT_035134mg.
DR KEGG; sita:101783343; -.
DR eggNOG; KOG0628; Eukaryota.
DR HOGENOM; CLU_011856_3_1_1; -.
DR InParanoid; K4A8C8; -.
DR OMA; FIRYAIC; -.
DR OrthoDB; 349065at2759; -.
DR Proteomes; UP000004995; Chromosome IX.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016831; F:carboxy-lyase activity; IBA:GO_Central.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 1.20.1340.10; dopa decarboxylase, N-terminal domain; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR010977; Aromatic_deC.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11999; GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE; 1.
DR PANTHER; PTHR11999:SF96; TYROSINE DECARBOXYLASE; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR PRINTS; PR00800; YHDCRBOXLASE.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW ECO:0000256|RuleBase:RU000382};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT MOD_RES 334
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ SEQUENCE 529 AA; 57762 MW; 9CC3CE533691969B CRC64;
MAPPSHCYIS NGAPQNGVVV PMETGTLPPQ DSHLLDPDEF RRQGHQVIDF IADYYARMGE
YPVHPSVNPG FLRRELPADA PSRPERDAFD AALRDVRDLI LPGLTHWQSP RHFAHFPASS
STVGALGEAL TAGINIVPFT WAASPAATEL EMVVVDWLGK ALHLPERLMF CGGGGGTLLG
TTCEAILCAL VAARDRKLAD IGSRRIGDLV VYCSDQTHFA FRKAAHIAGI HRDNCREIAT
CRDDVFALSP AELHAATQAD VDAGLVPLFL CATVGTTQTT AVDPIRELSA VAAAHGAWVH
VDAAYAGSAL VCPEFRHVID GVEAVDSFSM NAHKWLLANT DCCALWVRKP SLLVAALGTE
QEYILKDAAA EGHDVVDYKD WSVTLTRRFR ALKLWLVLRC YGVEGLRAHV RSHLRIAASF
ESMVRADARF EVTVATQFAL VCFRLRSPEK LGGEKTANEL NRRLLEEVNS TGSGPYMSSA
MVGGIYMLRC AVGSTLTEER HVREAWKVVQ DQAASLLRKM EINYSVVAE
//
