ID K4AAM3_SETIT Unreviewed; 407 AA.
AC K4AAM3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=NAD(P)-binding domain-containing protein {ECO:0000259|Pfam:PF16363};
GN Name=101768534 {ECO:0000313|EnsemblPlants:KQK91244};
GN ORFNames=SETIT_9G434100v2 {ECO:0000313|EMBL:RCV45197.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQK91244, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV45197.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK91244,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV45197.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV45197.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV45197.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK91244}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK91244};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR EMBL; AGNK02006021; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003536; RCV45197.1; -; Genomic_DNA.
DR RefSeq; XP_004984661.1; XM_004984604.2.
DR RefSeq; XP_012698261.1; XM_012842807.2.
DR AlphaFoldDB; K4AAM3; -.
DR STRING; 4555.K4AAM3; -.
DR EnsemblPlants; KQK91244; KQK91244; SETIT_035930mg.
DR GeneID; 101768534; -.
DR Gramene; KQK91244; KQK91244; SETIT_035930mg.
DR KEGG; sita:101768534; -.
DR eggNOG; KOG1371; Eukaryota.
DR HOGENOM; CLU_007383_1_10_1; -.
DR InParanoid; K4AAM3; -.
DR OMA; HEPGVIH; -.
DR OrthoDB; 49205at2759; -.
DR Proteomes; UP000004995; Chromosome IX.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IBA:GO_Central.
DR GO; GO:0033499; P:galactose catabolic process via UDP-galactose; IBA:GO_Central.
DR CDD; cd05247; UDP_G4E_1_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005886; UDP_G4E.
DR NCBIfam; TIGR01179; galE; 1.
DR PANTHER; PTHR43725:SF38; UDP-ARABINOSE 4-EPIMERASE 3-RELATED; 1.
DR PANTHER; PTHR43725; UDP-GLUCOSE 4-EPIMERASE; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 67..384
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
SQ SEQUENCE 407 AA; 44908 MW; 7A665508CC045B35 CRC64;
MIPLNRRSSL PRAGMEYFDA RRKPHNVAKI IAALVLTTLC IFVLKQSPGF GGNSVFSRHE
PGVIHVLVTG GAGYIGSHAS LRLLKDNYRV TIVDNLSRGN MGAVKVLQEL FPHPGRLQFI
FADLGDQKSV NKIFAENAFD AVMHFAAVAY VGESTLEPLR YYHNITSNTL LILEAMASHG
VKTLIYSSTC ATYGEPEKMP ITEATPQFPI NPYGKAKKMA EDIILDFSKS KGADMAVMIL
RYFNVIGSDP EGRLGEAPRP ELREHGRISG ACFDAALGII PGLKVKGRDY PTADGTCIRD
YIDVTDLVDA HVKALNKAEP RKVGIYNVGT GRGRSVNEFV DACKKATGVD IKIEYLSRRP
GDYAEVYSDP TKINKELNWT AQYTDLKESL SVAWRWQKSH PHGYGTN
//
