GenomeNet

Database: UniProt
Entry: K4AB81_SETIT
LinkDB: K4AB81_SETIT
Original site: K4AB81_SETIT 
ID   K4AB81_SETIT            Unreviewed;       383 AA.
AC   K4AB81;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   31-JUL-2019, entry version 32.
DE   RecName: Full=Arogenate dehydratase {ECO:0000256|RuleBase:RU363004};
DE            EC=4.2.1.91 {ECO:0000256|RuleBase:RU363004};
GN   Name=101761099 {ECO:0000313|EnsemblPlants:KQK91360};
OS   Setaria italica (Foxtail millet) (Panicum italicum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae;
OC   PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX   NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQK91360};
RN   [1] {ECO:0000313|EnsemblPlants:KQK91360}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK91360};
RX   PubMed=22580951; DOI=10.1038/nbt.2196;
RA   Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA   Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J.,
RA   Jenkins J., Barry K., Lindquist E., Hellsten U., Deshpande S.,
RA   Wang X., Wu X., Mitros T., Triplett J., Yang X., Ye C.Y.,
RA   Mauro-Herrera M., Wang L., Li P., Sharma M., Sharma R., Ronald P.C.,
RA   Panaud O., Kellogg E.A., Brutnell T.P., Doust A.N., Tuskan G.A.,
RA   Rokhsar D., Devos K.M.;
RT   "Reference genome sequence of the model plant Setaria.";
RL   Nat. Biotechnol. 30:555-561(2012).
RN   [2] {ECO:0000313|EnsemblPlants:KQK91360}
RP   IDENTIFICATION.
RC   STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK91360};
RG   EnsemblPlants;
RL   Submitted (AUG-2018) to UniProtKB.
CC   -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC       chorismate pathway into phenylalanine.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC         Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180;
CC         EC=4.2.1.91; Evidence={ECO:0000256|RuleBase:RU363004};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC       phenylalanine from L-arogenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC       {ECO:0000256|RuleBase:RU363004}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AGNK02006032; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EnsemblPlants; KQK91360; KQK91360; SETIT_036014mg.
DR   Gramene; KQK91360; KQK91360; SETIT_036014mg.
DR   eggNOG; KOG2797; Eukaryota.
DR   eggNOG; COG0077; LUCA.
DR   UniPathway; UPA00121; UER00344.
DR   ExpressionAtlas; K4AB81; baseline.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0047769; F:arogenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Chloroplast {ECO:0000256|RuleBase:RU363004};
KW   Lyase {ECO:0000256|RuleBase:RU363004};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU363004};
KW   Plastid {ECO:0000256|RuleBase:RU363004};
KW   Transit peptide {ECO:0000256|RuleBase:RU363004}.
FT   REGION       38     62       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     38     57       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   383 AA;  41525 MW;  A981FD90B7C7EADD CRC64;
     MAPTACLRLP FLPARARGHS ATSPSSRRPA LTLKCSAAAN GDSSKPNSIS ISPTSPPRGT
     VADGVESVDV NGLRRPPVPV SGLTVPGARD PHWLRRPLTS ADVMEVNGKG LKVAYQGCPG
     AYSEAAARKA YPNCETVPCE HFDTAFQAVQ NWVADRAVLP LENSLGGSIH RNYDLLLRHS
     LHIVGEVRLA VRHCLLANPG VEIENLKSAM SHPQALAQCE HTLTGLGIEH REAVDDTAGA
     AKFVAEQMLQ DTGAIASSLA AKLYGLDVLA ENIQDDKDNV TRFMMLAREP IIPRTDKPFK
     TSIVFSLEEG PGQLFKALAV FALREINLTK IESRPHKERP LRVSDDCLIK NFDYLFYVDL
     EASMADPKTQ NALGNLKVSL QPF
//
DBGET integrated database retrieval system