ID K4ADD8_SETIT Unreviewed; 288 AA.
AC K4ADD8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Gnk2-homologous domain-containing protein {ECO:0000259|PROSITE:PS51473};
GN Name=101782146 {ECO:0000313|EnsemblPlants:KQK92643};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQK92643, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQK92643, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQK92643,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQK92643}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQK92643};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, plasmodesma
CC {ECO:0000256|ARBA:ARBA00024184}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004251}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the cysteine-rich repeat secretory protein
CC family. Plasmodesmata-located proteins (PDLD) subfamily.
CC {ECO:0000256|ARBA:ARBA00038393}.
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DR EMBL; AGNK02006131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004985760.2; XM_004985703.2.
DR AlphaFoldDB; K4ADD8; -.
DR STRING; 4555.K4ADD8; -.
DR EnsemblPlants; KQK92643; KQK92643; SETIT_036895mg.
DR GeneID; 101782146; -.
DR Gramene; KQK92643; KQK92643; SETIT_036895mg.
DR KEGG; sita:101782146; -.
DR eggNOG; ENOG502QUWZ; Eukaryota.
DR HOGENOM; CLU_000288_33_1_1; -.
DR InParanoid; K4ADD8; -.
DR OMA; YLEKCYI; -.
DR OrthoDB; 621052at2759; -.
DR Proteomes; UP000004995; Chromosome IX.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0010497; P:plasmodesmata-mediated intercellular transport; IBA:GO_Central.
DR GO; GO:0046739; P:transport of virus in multicellular host; IBA:GO_Central.
DR Gene3D; 3.30.430.20; Gnk2 domain, C-X8-C-X2-C motif; 2.
DR InterPro; IPR002902; GNK2.
DR InterPro; IPR038408; GNK2_sf.
DR PANTHER; PTHR32080; ANTIFUNGAL PROTEIN GINKBILOBIN-2-LIKE; 1.
DR PANTHER; PTHR32080:SF24; PLASMODESMATA-LOCATED PROTEIN 3; 1.
DR Pfam; PF01657; Stress-antifung; 2.
DR PROSITE; PS51473; GNK2; 2.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..288
FT /note="Gnk2-homologous domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010128812"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..136
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 141..241
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
SQ SEQUENCE 288 AA; 29428 MW; 1F94E5D9E4B16C10 CRC64;
MGRARRFLLA AAAAAVFLLL HAPPLVSCAD LDALVYKGCA NQSFPGGALP PTVAVLSSAL
SAQAGSTKFY KTSSPSSSGS STSVFGLFQC RGDLSGSDCA SCVSRAMSSW RDVCGASVAA
RVQLTGCLAL YEVSGFPQVS GVQMLFKTCG TGSGGGGDFE MRRDTAFAAL EGGVATSNGG
FIATSYQAVY AMAQCEGDLS TADCGQCVTQ AVQHVEVECG GAPSGQVYLD KCYISYSYYP
HGVPHGGGMG GQQTAKTVAI VLGGAVGVGF LVICLLFARS LVKKKDDY
//
