ID K4L6N9_9FIRM Unreviewed; 848 AA.
AC K4L6N9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Cadmium-transporting ATPase {ECO:0000313|EMBL:AFV06266.1};
DE EC=3.6.3.3 {ECO:0000313|EMBL:AFV06266.1};
GN ORFNames=DCF50_p2263 {ECO:0000313|EMBL:AFV06266.1};
OS Dehalobacter sp. CF.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Dehalobacter.
OX NCBI_TaxID=1131462 {ECO:0000313|EMBL:AFV06266.1, ECO:0000313|Proteomes:UP000000482};
RN [1] {ECO:0000313|EMBL:AFV06266.1, ECO:0000313|Proteomes:UP000000482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AFV06266.1};
RX PubMed=23284863; DOI=10.1371/journal.pone.0052038;
RA Tang S., Gong Y., Edwards E.A.;
RT "Semi-automatic in silico gap closure enabled de novo assembly of two
RT dehalobacter genomes from metagenomic data.";
RL PLoS ONE 7:E52038-E52038(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003870; AFV06266.1; -; Genomic_DNA.
DR RefSeq; WP_015044301.1; NC_018867.1.
DR AlphaFoldDB; K4L6N9; -.
DR STRING; 1131462.DCF50_p2263; -.
DR KEGG; dec:DCF50_p2263; -.
DR PATRIC; fig|1131462.4.peg.2280; -.
DR eggNOG; COG0474; Bacteria.
DR HOGENOM; CLU_002360_3_3_9; -.
DR Proteomes; UP000000482; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 2.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 2.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF156; CALCIUM-TRANSPORTING ATPASE; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:AFV06266.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000482};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 641..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 712..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 749..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 788..807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 819..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..65
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 848 AA; 93140 MW; 8C468E04BC48AAAD CRC64;
MTEQQIRELQ GLSSSEARQL QERFGKNELV PEKKESFPHK ILQVISEPMF LLLLIAAVIY
FILGEPRDGA IMLVFVVGII SIEVIQEWKT DQTLRALKDL STPKISVLRD GMMQIINSSD
LVPGDIMFIA EGVKVPADGT VLKASTLCVD ESSLTGESAG VWKVVYGDKA ANGELSLDSK
EYWRRDYCYA GTLVTQGTGT IRVDQIGPAT EYGKIGQEIA AAPDRPTPLE KQTGKLVKLC
AGIAAVLFAL VGVVTYFNLP DHVGSERVIE SILSGITLAM AMIPEEFPVI LTVFLSMGAW
RLAKKQSLVR RLSSVETLGA VSVLCVDKTG TITMNQMTVR DTWSLNDDGK GLIRIMGMGC
EPDAYDPMEK AMIAYCEVQG IGRELLFGGE LIKEYAFTDQ TKMMGHVWQN ENELVVAAKG
SPERILDVCS LTDQERKVAE HKIREMSQQG LRVIAVGQMV LAGKEEVPDT LPECRLQLCG
MVGLADPPRE SVKQDIQICN KAGVRVVMIT GDNGITASTI ARQINMPNCD KIITGDELNQ
MSEEELREKV KDVSIFSRVI PEHKMRIVKA FKDNGEIVAM TGDGVNDAPA LKYADIGIAM
GKRGSEVSRE AADLVLLDDN FSTIVDTIKD GRRIYDNIRK AVGYVFTIHI PIAFASLLAP
FLGISPASLL LLPLHVVLLE VVIDPTCSIV LERQPAERDI MDQPPRNPNE KLLTAKILSK
SVLQGLVIFG ASFGTYFTVL NNHPDQASLA RTMALAIILL ANLVLVQVNS SNTDSAFRSF
AKLIRDKVMW MVNIGTIAGL LLIIYTPLNH LLKLAPLSWK QLILAAALAV VSVGWYEVVK
GFKRWKRT
//
